DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ovo and OVOL3

DIOPT Version :9

Sequence 1:	NP_001162673.1	Gene:	ovo / 31429	FlyBaseID:	FBgn0003028	Length:	1351	Species:	Drosophila melanogaster
Sequence 2:	XP_016882679.1	Gene:	OVOL3 / 728361	HGNCID:	14186	Length:	213	Species:	Homo sapiens

Alignment Length:	153	Identity:	75/153 - (49%)
Similarity:	98/153 - (64%)	Gaps:	8/153 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly  1166 SSNASSHGSAEALCMGS--------SGGANEDSSSGNNKFVCRVCMKTFSLQRLLNRHMKCHSDI 1222
            ||:.||.|...|....|        :.|....:..|.....|.:|.|.|.|||:|.||:||||.:
Human    54 SSDCSSLGGPPAQQSSSVRDPWTAPTQGNLTSAPRGPGTLGCPLCPKAFPLQRMLTRHLKCHSPV 118

  Fly  1223 KRYLCTFCGKGFNDTFDLKRHTRTHTGVRPYKCNLCEKSFTQRCSLESHCQKVHSVQHQYAYKER 1287
            :|:||..|||||:|.||||||.|||||:||::|:.|.|:||||||||:|..|||.....|||:||
Human   119 RRHLCRCCGKGFHDAFDLKRHMRTHTGIRPFRCSACGKAFTQRCSLEAHLAKVHGQPASYAYRER 183

  Fly  1288 RAKMYVCEECGHTTCEPEVHYLH 1310
            |.|::|||:||.|:..|:.:..|
Human   184 REKLHVCEDCGFTSSRPDTYAQH 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ovo	NP_001162673.1	C2H2 Zn finger	1199..1219	CDD:275368	11/19 (58%)
		zf-H2C2_2	1212..1235	CDD:290200	14/22 (64%)
		C2H2 Zn finger	1227..1247	CDD:275368	14/19 (74%)
		zf-H2C2_2	1239..1264	CDD:290200	16/24 (67%)
		C2H2 Zn finger	1255..1276	CDD:275368	13/20 (65%)
OVOL3	XP_016882679.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3576
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001339
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10032
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910