DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ovo and OVOL2

DIOPT Version :9

Sequence 1:NP_001162673.1 Gene:ovo / 31429 FlyBaseID:FBgn0003028 Length:1351 Species:Drosophila melanogaster
Sequence 2:NP_067043.2 Gene:OVOL2 / 58495 HGNCID:15804 Length:275 Species:Homo sapiens


Alignment Length:217 Identity:104/217 - (47%)
Similarity:128/217 - (58%) Gaps:44/217 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly  1161 SNSSASSNASSHGSAEALCMGSSGGANEDS---------------------SSGNNKFV------ 1198
            |:.|.||:|...|.||:   .||..|.|..                     :....||.      
Human    54 SSGSGSSSAGEPGGAES---SSSPHAPESETPEPGDAEGPDGHLATKQRPVARSKIKFTTGTCSD 115

  Fly  1199 -----CRVCMKTFSLQRLLNRHMKCHSDIKRYLCTFCGKGFNDTFDLKRHTRTHTGVRPYKCNLC 1258
                 |.:|.|.|.|||:||||:|||:.:||:||||||||||||||||||.|||||:||||||:|
Human   116 SVVHSCDLCGKGFRLQRMLNRHLKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCNVC 180

  Fly  1259 EKSFTQRCSLESHCQKVHSVQHQYAYKERRAKMYVCEECGHTTCEPEVHYLHLKNNHPFSPALLK 1323
            .|:||||||||||.:|:|.||.|||||:||.|:||||:||:|....|..|||:.:.||.|..|.|
Human   181 NKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNSAHPGSSFLKK 245

  Fly  1324 FYDKRHFKFTNSQFANNLLGQL 1345
                     |:.:.|..|.|:|
Human   246 ---------TSKKLAALLQGKL 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ovoNP_001162673.1 C2H2 Zn finger 1199..1219 CDD:275368 12/19 (63%)
zf-H2C2_2 1212..1235 CDD:290200 17/22 (77%)
C2H2 Zn finger 1227..1247 CDD:275368 18/19 (95%)
zf-H2C2_2 1239..1264 CDD:290200 19/24 (79%)
C2H2 Zn finger 1255..1276 CDD:275368 15/20 (75%)
OVOL2NP_067043.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 15..101 12/49 (24%)
C2H2 Zn finger 121..141 CDD:275368 12/19 (63%)
C2H2 Zn finger 149..169 CDD:275368 18/19 (95%)
zf-H2C2_2 161..186 CDD:316026 19/24 (79%)
C2H2 Zn finger 177..198 CDD:275368 15/20 (75%)
C2H2 Zn finger 216..233 CDD:275368 8/16 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3576
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001339
OrthoInspector 1 1.000 - - otm40732
orthoMCL 1 0.900 - - OOG6_105449
Panther 1 1.100 - - O PTHR10032
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3205
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
76.840

Return to query results.
Submit another query.