DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ovo and ovol2

DIOPT Version :9

Sequence 1:	NP_001162673.1	Gene:	ovo / 31429	FlyBaseID:	FBgn0003028	Length:	1351	Species:	Drosophila melanogaster
Sequence 2:	NP_001004998.1	Gene:	ovol2 / 448478	XenbaseID:	XB-GENE-854193	Length:	287	Species:	Xenopus tropicalis

Alignment Length:	238	Identity:	102/238 - (42%)
Similarity:	132/238 - (55%)	Gaps:	36/238 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1106 IDCI------DDLSKHG-------HHSQHQQQQGS-------PQQQNMQQSVQQQSVQQQQSLQQ 1150
            ||||      |.||...       ...:.....||       |.....|..:...|.:.....:.
Frog    36 IDCIFKYVTEDSLSNSSAGDPAGDSPERSSSDSGSCNGSITTPPHNTPQSGLVSPSRKDSTKQED 100

  Fly  1151 QQQQQHHQHHSNSSASSNASSHGSAEALCMGSSGGANEDSSSGNNKFVCRVCMKTFSLQRLLNRH 1215
            :::|....|....||.|....          ::|..:|:..|      |.:|.|.|.|||:||||
Frog   101 EEEQTSDPHGKRPSARSKIKF----------TTGSCSEEIYS------CEICAKGFRLQRMLNRH 149

  Fly  1216 MKCHSDIKRYLCTFCGKGFNDTFDLKRHTRTHTGVRPYKCNLCEKSFTQRCSLESHCQKVHSVQH 1280
            :|||:.:||:||||||||||||||||||.|||||:|||||.:|.|:||||||||||.:|:|.||.
Frog   150 LKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCEICNKAFTQRCSLESHLKKIHGVQQ 214

  Fly  1281 QYAYKERRAKMYVCEECGHTTCEPEVHYLHLKNNHPFSPALLK 1323
            .||||:||.|::|||:||:|....|..|||:.::||.|..|.|
Frog   215 GYAYKQRRDKLFVCEDCGYTGPSQEDLYLHVYDSHPGSAFLKK 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ovo	NP_001162673.1	C2H2 Zn finger	1199..1219	CDD:275368	12/19 (63%)
		zf-H2C2_2	1212..1235	CDD:290200	17/22 (77%)
		C2H2 Zn finger	1227..1247	CDD:275368	18/19 (95%)
		zf-H2C2_2	1239..1264	CDD:290200	18/24 (75%)
		C2H2 Zn finger	1255..1276	CDD:275368	14/20 (70%)
ovol2	NP_001004998.1	C2H2 Zn finger	133..153	CDD:275368	12/19 (63%)
		zf-H2C2_2	145..169	CDD:372612	17/23 (74%)
		C2H2 Zn finger	161..181	CDD:275368	18/19 (95%)
		zf-H2C2_2	173..198	CDD:372612	18/24 (75%)
		zf-C2H2_3rep	189..>250	CDD:376287	34/60 (57%)
		C2H2 Zn finger	189..210	CDD:275368	14/20 (70%)
		C2H2 Zn finger	228..245	CDD:275368	8/16 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001339
OrthoInspector	1	1.000	-	-		otm47916
Panther	1	1.100	-	-	O	PTHR10032
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3205
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.040