DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ovo and Zfp266

DIOPT Version :9

Sequence 1:	NP_001162673.1	Gene:	ovo / 31429	FlyBaseID:	FBgn0003028	Length:	1351	Species:	Drosophila melanogaster
Sequence 2:	NP_001128490.1	Gene:	Zfp266 / 367034	RGDID:	1308643	Length:	604	Species:	Rattus norvegicus

Alignment Length:	221	Identity:	58/221 - (26%)
Similarity:	86/221 - (38%)	Gaps:	69/221 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1163 SSASSNASSHGSAEALCMGSSGGANEDSSSGNNKFVCRVCMKTFSLQRLLNRHMKCHSDIKRYLC 1227
            |..|::..:|              ||:     ..|||:.|.|.|.....||.|::.|:.||.|.|
  Rat   356 SRLSAHVKTH--------------NEE-----KPFVCKECGKAFKNMSYLNDHVRIHTGIKSYKC 401

  Fly  1228 TFCGKGF------------------------NDTF----DLKRHTRTHTGVRPYKCNLCEKSFTQ 1264
            ..|||.|                        ..||    .|..|.|||||::||:|..|.|:|||
  Rat   402 MECGKAFLRWSGLTEHIRVHTGEKPYECKECGKTFSRSTQLTEHIRTHTGIKPYECKECGKAFTQ 466

  Fly  1265 RCSLESHCQKVHSVQHQYAYKERRAKMYVCEECG--HTTCEPEVHYLHLKNNH-PF------SPA 1320
            ...|.:|. ::||.:          |.:.|:|||  .|.....:|::...... ||      ...
  Rat   467 YSGLATHV-RIHSGE----------KPFACKECGKAFTRTSGLIHHVRTHTGEKPFECVHCGKTF 520

  Fly  1321 LLKFYDKRHFKFTNSQ--FANNLLGQ 1344
            :...:..:|.|..:.:  |..|:.|:
  Rat   521 ITSSHRTKHLKIHSGEKPFVCNICGK 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ovo	NP_001162673.1	C2H2 Zn finger	1199..1219	CDD:275368	7/19 (37%)
		zf-H2C2_2	1212..1235	CDD:290200	12/46 (26%)
		C2H2 Zn finger	1227..1247	CDD:275368	10/47 (21%)
		zf-H2C2_2	1239..1264	CDD:290200	13/24 (54%)
		C2H2 Zn finger	1255..1276	CDD:275368	8/20 (40%)
Zfp266	NP_001128490.1	KRAB	41..97	CDD:214630
		C2H2 Zn finger	265..281	CDD:275368
		C2H2 Zn finger	289..309	CDD:275368
		C2H2 Zn finger	317..337	CDD:275368
		C2H2 Zn finger	345..365	CDD:275368	2/8 (25%)
		zf-C2H2	371..393	CDD:395048	9/21 (43%)
		C2H2 Zn finger	373..393	CDD:275368	7/19 (37%)
		COG5048	<397..588	CDD:227381	42/161 (26%)
		C2H2 Zn finger	401..421	CDD:275368	5/19 (26%)
		C2H2 Zn finger	429..449	CDD:275368	5/19 (26%)
		C2H2 Zn finger	457..477	CDD:275368	8/20 (40%)
		C2H2 Zn finger	485..505	CDD:275368	6/19 (32%)
		C2H2 Zn finger	513..533	CDD:275368	2/19 (11%)
		C2H2 Zn finger	541..561	CDD:275368	2/6 (33%)
		C2H2 Zn finger	569..589	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910