DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ovo and Ovol2

DIOPT Version :9

Sequence 1:	NP_001162673.1	Gene:	ovo / 31429	FlyBaseID:	FBgn0003028	Length:	1351	Species:	Drosophila melanogaster
Sequence 2:	XP_038960525.1	Gene:	Ovol2 / 296201	RGDID:	1306130	Length:	274	Species:	Rattus norvegicus

Alignment Length:	222	Identity:	101/222 - (45%)
Similarity:	128/222 - (57%)	Gaps:	46/222 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1161 SNSSASSNASSHGSAEAL---------------CMGSSG------------------GANEDSSS 1192
            |:|..|.:|...|.||:.               ..|:.|                  |...||..
  Rat    53 SSSGCSCSAGEPGGAESSSSPRAPEPETPELHDAEGTDGHLAAMQRPVARSKIKFTTGTCNDSVI 117

  Fly  1193 GNNKFVCRVCMKTFSLQRLLNRHMKCHSDIKRYLCTFCGKGFNDTFDLKRHTRTHTGVRPYKCNL 1257
            .|    |.:|.|:|.|||:||||:|||:.:||:||||||||||||||||||.|||||:|||||.:
  Rat   118 HN----CDLCGKSFRLQRMLNRHLKCHNQVKRHLCTFCGKGFNDTFDLKRHVRTHTGIRPYKCEV 178

  Fly  1258 CEKSFTQRCSLESHCQKVHSVQHQYAYKERRAKMYVCEECGHTTCEPEVHYLHLKNNHPFSPALL 1322
            |.|:||||||||||.:|:|.||.|||||:||.|:||||:||:|....|..|||:.:.||.|..|.
  Rat   179 CYKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCEDCGYTGPTQEDLYLHVNSAHPGSTFLK 243

  Fly  1323 KFYDKRHFKFTNSQFANNLLGQLPMPV 1349
            |         |:.:.|..:..:|..|:
  Rat   244 K---------TSKKLAALMQNKLTSPL 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ovo	NP_001162673.1	C2H2 Zn finger	1199..1219	CDD:275368	12/19 (63%)
		zf-H2C2_2	1212..1235	CDD:290200	17/22 (77%)
		C2H2 Zn finger	1227..1247	CDD:275368	18/19 (95%)
		zf-H2C2_2	1239..1264	CDD:290200	18/24 (75%)
		C2H2 Zn finger	1255..1276	CDD:275368	14/20 (70%)
Ovol2	XP_038960525.1	COG5048	118..>169	CDD:227381	37/54 (69%)
		C2H2 Zn finger	120..140	CDD:275368	12/19 (63%)
		C2H2 Zn finger	148..168	CDD:275368	18/19 (95%)
		zf-H2C2_2	160..185	CDD:404364	18/24 (75%)
		zf-C2H2_3rep	176..>237	CDD:408638	36/60 (60%)
		C2H2 Zn finger	176..197	CDD:275368	14/20 (70%)
		C2H2 Zn finger	215..232	CDD:275368	8/16 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3576
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001339
OrthoInspector	1	1.000	-	-		otm44871
orthoMCL	1	0.900	-	-		OOG6_105449
Panther	1	1.100	-	-	O	PTHR10032
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.810