DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ovo and si:ch73-144d13.5

DIOPT Version :9

Sequence 1:	NP_001162673.1	Gene:	ovo / 31429	FlyBaseID:	FBgn0003028	Length:	1351	Species:	Drosophila melanogaster
Sequence 2:	XP_017206607.2	Gene:	si:ch73-144d13.5 / 100004091	ZFINID:	ZDB-GENE-131120-187	Length:	396	Species:	Danio rerio

Alignment Length:	322	Identity:	68/322 - (21%)
Similarity:	100/322 - (31%)	Gaps:	132/322 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly  1123 QQQGSPQQQNM-----------QQSVQQQSVQQQQSLQQQQQQQHHQHHSNSSASSNASSHGSAE 1176
            :.:|.||.:|.           ..:.:..|:::.|....||..:         ..||..:|
Zfish    53 EMKGEPQYENQNFIAEGKYFSCSNNEKTLSIKRAQDTGSQQCDK---------TISNKINH---- 104

  Fly  1177 ALCMGSSGGANEDSSS--------------------GNNKFVCRVCMKTFSLQRLLNRHMKCHSD 1221
            ..|:.|..|....:.|                    |...|.|:.|.|:||.:..|.||:|.|::
Zfish   105 ERCVKSRKGKKSYTCSLCGKSFKHTGHFKDHMRIHTGEKPFTCQQCGKSFSRKITLQRHVKIHNE 169

  Fly  1222 IKRYL--------------------------------------------------------CTFC 1230
            .|.|:                                                        |..|
Zfish   170 EKPYMCHQCGKSFIQKGYLKVHMKVHTGEKPYTCPQCGRGFIQKGNYRVHMRIHSEEKQHTCPHC 234

  Fly  1231 GKGFNDTFDLKRHTRTHTGVRPYKCNLCEKSFTQRCSLESHCQKVHSVQHQ-------------- 1281
            ||.||....|:.|.|||||.:||.|.||.|||.|:.:...| .::||.:.|
Zfish   235 GKSFNQAGHLRDHIRTHTGEKPYTCPLCGKSFIQKGNYRVH-MRIHSEEKQNTCPQCGKSFNQTG 298

  Fly  1282 ----YAYKERRAKMYVCEECG-------HTTCEPEVHYLHLKNNHPFSPALL--KFYDKRHF 1330
                :.......|.|.|.:||       |.|....:|    ....|::.|..  .|..|.|:
Zfish   299 HLRDHIRTHTGEKPYTCAQCGKGFNQKSHYTVHMRIH----SEEKPYNCAQCGKSFNQKVHY 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ovo	NP_001162673.1	C2H2 Zn finger	1199..1219	CDD:275368	9/19 (47%)
		zf-H2C2_2	1212..1235	CDD:290200	11/78 (14%)
		C2H2 Zn finger	1227..1247	CDD:275368	9/19 (47%)
		zf-H2C2_2	1239..1264	CDD:290200	15/24 (63%)
		C2H2 Zn finger	1255..1276	CDD:275368	8/20 (40%)
si:ch73-144d13.5	XP_017206607.2	C2H2 Zn finger	92..111	CDD:275368	6/31 (19%)
		C2H2 Zn finger	119..139	CDD:275368	1/19 (5%)
		zf-H2C2_2	131..156	CDD:316026	6/24 (25%)
		RecG	<145..>207	CDD:333223	13/61 (21%)
		C2H2 Zn finger	147..167	CDD:275368	9/19 (47%)
		C2H2 Zn finger	175..195	CDD:275368	0/19 (0%)
		COG5048	<199..350	CDD:227381	36/155 (23%)
		C2H2 Zn finger	203..223	CDD:275368	0/19 (0%)
		C2H2 Zn finger	231..251	CDD:275368	9/19 (47%)
		C2H2 Zn finger	259..279	CDD:275368	8/20 (40%)
		C2H2 Zn finger	287..307	CDD:275368	0/19 (0%)
		C2H2 Zn finger	315..335	CDD:275368	5/19 (26%)
		C2H2 Zn finger	343..363	CDD:275368	4/14 (29%)
		zf-H2C2_2	359..380	CDD:316026
		C2H2 Zn finger	371..391	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910