Protein Alignment Ptp4E and Ptprj

DIOPT Version :10

• Sequence 1: NP_525076.2
• Gene: Ptp4E / 31425
• FlyBaseID: FBgn0004368
• Length: 1767
• Species: Drosophila melanogaster
• Sequence 2: XP_038960584.1
• Gene: Ptprj / 29645
• RGDID: 3454
• Length: 1352
• Species: Rattus norvegicus
• Alignment Length: 1624
• Identity: 380/1624 - (23%)
• Similarity: 612/1624 - (37%)
• Gaps: 472/1624 - (29%)

  Fly   151 PDPPANLSVQLR---SSKSAFITWRPPGSG----RYSGFRIRVLGLTDLPFERSYSLEGNETLQL 208
            |.|....|.:||   ::.:|.::...||:|    |.:|:|.|                 ....:|
  Rat    40 PRPLRVRSARLRRVAAAAAAAMSPGKPGAGGAGTRRTGWRRR-----------------RRRRRL 87

  Fly   209 SAKELTPG-GSYQVQAYSVYQGKESVAYTSRNFTTKPNTPGKFIVW------------------- 253
            .|:...|| |....:....:||.:.:...:|...|.|.:||  :.|
  Rat    88 EAETRAPGFGHTAGRVPGTFQGAQGMKPAARETRTPPRSPG--LRWALLPLLLLLRQGQVVCAGA 150

  Fly   254 ----------FRNETTLLVLWQPPFPAGIYTHYRVSITPDDAI---QSVLYVEREGEPPGPAQAA 305
                      ..:.|::::.|:          :..|.|.:..|   .::.|..:.       |.:
  Rat   151 APSPVFDVEAVTSPTSVVLTWK----------HNDSATSEYKINEGNTLRYTVKN-------QTS 198

  Fly   306 FK--GLVPGREYNISVQTVSEDETSSVPTTARYLTVPERVLNVTFDEAYTTSSSFRVRWEPPRTY 368
            |.  ||.|...|..|:...:.:|||..||.....|.|..|            |..:|.:
  Rat   199 FNITGLSPATSYKFSITLGTVNETSGKPTYKNITTEPWPV------------SDLQVAY------ 245

  Fly   369 SEFDAYQVMLSTSRRIFNVPRAANGDSVYFDYPDILEPGRTYEVVVKTIADNVNSWPASGEVT-L 432
              ....|.:|:.|.        |||.:             :|.:.:..:..|     :||.:: |
  Rat   246 --IGVTQALLAWSN--------ANGTA-------------SYRMQIVELTTN-----SSGGISDL 282

  Fly   433 RPRPVRSLGGFLDDRSNALHISWEPAETGRQDSYRISYHEQTNASEVPAPFPVAAESQITTN--- 494
            :|...:||.  :...:...|..|  ...|..|:         |.:|   ..|||..||:..|
  Rat   283 KPGTHKSLA--VQGSNETQHDLW--VTEGVSDA---------NGTE---GSPVANISQLHKNSLA 331

  Fly   495 -----------LTEYTLDSLLAGRRYLIAVQALSKGVASNASDITR--------YTRPAAPLIQE 540
                       |||..|..|....:|.:.:.       |.|:|.|.        .|.|..  :.:
  Rat   332 SADPPSARDPSLTEVLLTELKPDTQYKVTIY-------SQAADGTEGQPGNKVFKTNPIQ--VSD 387

  Fly   541 LRSI---DQGLMLSWRSDVNSRQDRYEVHYQRNGTREERTMATNETSLTIHYLHPGSGYEVKVHA 602
            :|::   |..:.|:|:|:.|.....:.......|..:......|||...|..|...:.|.:.|..
  Rat   388 IRAVNISDSNMTLTWKSNNNESHASFTYKIYVAGGSDSINETVNETQAVIRGLSSSTLYNITVLP 452

  Fly   603 ISHGVRSEPHSYFQAVF--PKPPQNLTLQTVHTNLVVLHWQAPEGSDFSEYVVRYRTDASPWQRI 665
            ........|.  |..|:  |:|..:..:..|....:.|.|::.:...|..::.:..:: ..|...
  Rat   453 FLGQTAGIPG--FLQVYTSPRPVSDFRVTNVSLREIGLAWRSNDSESFEIFITQEGSE-KRWNAS 514

  Fly   666 SGLHENEARIKDMHY-------GERYLVQVNTVSF-----GVESPHPLELNVTMPPQPVSNVVPL 718
            :|         |:.|       |..|..::    |     |.|.|....:..|.........|..
  Rat   515 TG---------DLSYIVENLKPGTSYQFEI----FPRGPNGTEGPSQTVVGRTDCSAVTDIRVVS 566

  Fly   719 VDSRNLTLEWPRPDGHVDFYTLKWWPTDEEDRVEFKNVTQLED----LSSPSVRIPIEDLSPGRQ 779
            |.:..:.|||..              ||......:..|.:.|:    .:|....|.:..|:||..
  Rat   567 VSTTEIQLEWQN--------------TDSASGYTYHLVLESENGSIKTNSSQKWITVGGLTPGTL 617

  Fly   780 YRFEVQASSNGIRSGTTHLSTRTMPLIQSDVFIANAGHEQGQDET----ITLSYTPTPADSTRFD 840
            |...:....:.:...::.::..|.|        :|..:.:....|    |........:.|..:.
  Rat   618 YNVTIFPEVDQMEGNSSSITQYTRP--------SNVSYIEVNTNTTVAAIQWKNLDAASASYSYS 674

  Fly   841 IYRFSMGDPTIKDKEKLANDTER-----KLSFSGLTPGKLYNVTVWTVSGGVA---SLPVQRLYR 897
            :.....||.        :|.|.|     .::..||.||..|.|.::|......   .:|.|:|:.
  Rat   675 VLILKAGDG--------SNVTSRVRDIPSVTIPGLIPGVSYEVKIFTKIRNTEVGNEVPGQKLFC 731

  Fly   898 LHPLPISDLKAIQVAARE--ITLHWTAPAGEYTDFELQYLSADEEAPQLLQNVTKN------TEI 954
            :.|..:..|.. :|..:|  :.|.|..|.|..:.|||...|...:....|:|.|.:      ||:
  Rat   732 MEPAQVDSLHC-EVVPKEPALVLKWACPPGMNSGFELGVRSDAWDNMTHLENCTLDNDTECRTEV 795

  Fly   955 TLQGLRPYHNYTFTVVVRSGSIQGTDFADVSVSTLM--RSSAPISASYQT-LTAPPGKVDYFQPS 1016
            |      |.|::            |.: ::|::||.  :.:.|..::..| :|.||
  Rat   796 T------YLNFS------------TSY-NISIATLSCGKMALPTQSTCTTGITDPP--------- 832

  Fly  1017 DVQPGEVTFEWSLEPAEQHGPIDYFRITCQNADDAADVSSYEFPVNATQGKIDGLVPGNHYIFRI 1081
                                                                             
  Rat   833 ----------------------------------------------------------------- 832

  Fly  1082 QAKSALGYGAEREHIQTMPILAPPVPEPSVTPLEVSRTSSTIEISFRQGYFSNAHGMVRSYTIII 1146
                                  ||...|::|  .||..|..::.|    .|..:||.:::|.:::
  Rat   833 ----------------------PPDGSPNIT--SVSHNSVKVKFS----GFEASHGPIKAYAVLL 869

  Fly  1147 AE-DVGKNASGLEMPSWQDVQAYTVWLPYQ-----AIEPYNPFL---TSNGSRKSSLEAEHFTIG 1202
            .. :.|:       || .||..||    |:     |.:.|..:|   ...|..:...||.::.|.
  Rat   870 TTGEAGQ-------PS-TDVLKYT----YEDFKKGASDTYVTYLIRIEEKGQSQGLSEALNYEID 922

  Fly  1203 TANCDKHQAGYCNGPLRAGTTYRIKIRAFT--------------DEDKFTDTVYSSPITTERSDT 1253
            ..| .....||.||.|....:||..:..||              ||...:.:.||..::..:...
  Rat   923 VGN-QSTTLGYYNGRLEPLGSYRACVAGFTNITYNLQNDGLINGDESYVSFSPYSEAVSLPQDPG 986

  Fly  1254 VIVAAT----VSAVLLVAMVLVVVYCQHR----------CQLIRRASKLARMQDELAALPEGYIT 1304
            ||..|.    ..|:.:||:...:.:.:.|          .|:..:.|||.|
  Rat   987 VICGAVFGCIFGALAIVAVGGFIFWRKKRKDAKNNEVSFSQIKPKKSKLIR-------------- 1037

  Fly  1305 PNRPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSR 1369
                  |::|..:::...|||:..|:||:|:||.:|.......|.:..||.|||:.|:||||.||
  Rat  1038 ------VENFEAYFKKQQADSNCGFAEEYEDLKLIGISLPKYAAEIAENRGKNRYNNVLPYDISR 1096

  Fly  1370 FKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKG 1434
            .||. |......||||||||||::|.::||.|||||.:|.::||||.||.|..||||||:|.|:|
  Rat  1097 VKLS-VQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQG 1160

  Fly  1435 REKCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMVS--RNCESRIMRHFHFTTWPDFGVP 1497
            |.||::||| .:.|..||||.|.:..:....:|:|.:|:|.  ::.||..:|.||||:|||.|||
  Rat  1161 RTKCEEYWP-SKQAQDYGDITVAMTSEVVLPEWTIRDFVVKNMQSSESHPLRQFHFTSWPDHGVP 1224

  Fly  1498 EPPQSLVRF---VRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFA 1559
            :....|:.|   ||.:...|..: .||:|||||||||:|||||:||::..|...:.||::|||:.
  Rat  1225 DTTDLLINFRYLVRDYMKQIPPE-SPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYD 1288

  Fly  1560 MRKERVFMVQTEQQYVCIHQCLLAVLEGKEHLLADSLELHANDGYEVT---KIYLERQPQTKMG 1620
            :|..|..|||||.|||.::||:|.::..::....|.:       |:.|   .||...:|.:..|
  Rat  1289 LRMHRPLMVQTEDQYVFLNQCVLDIIRAQKDSKVDLI-------YQNTTAMTIYENLEPVSMFG 1345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp4E	NP_525076.2	FN3	<94..>334	CDD:442628	44/224 (20%)
		fn3	247..328	CDD:394996	17/114 (15%)
		FN3	319..>749	CDD:442628	89/469 (19%)
		fn3	708..796	CDD:394996	15/91 (16%)
		fn3	902..978	CDD:394996	19/83 (23%)
		fn3	1013..1092	CDD:394996	0/78 (0%)
		PTP_tm	1127..1247	CDD:465889	33/142 (23%)
		R3-PTPc	1358..1579	CDD:350396	114/225 (51%)
Ptprj	XP_038960584.1	FN3	169..659	CDD:442628	113/615 (18%)
		fn3	642..719	CDD:394996	17/92 (18%)
		PTP_tm	850..980	CDD:465889	34/146 (23%)
		R-PTPc-J	1084..1312	CDD:350463	117/230 (51%)