Protein Alignment Ptp4E and pyp2

DIOPT Version :9

• Sequence 1: NP_001162669.1
• Gene: Ptp4E / 31425
• FlyBaseID: FBgn0004368
• Length: 1767
• Species: Drosophila melanogaster
• Sequence 2: NP_594899.1
• Gene: pyp2 / 2542200
• PomBaseID: SPAC19D5.01
• Length: 711
• Species: Schizosaccharomyces pombe
• Alignment Length: 575
• Identity: 148/575 - (25%)
• Similarity: 237/575 - (41%)
• Gaps: 155/575 - (26%)

  Fly  1098 TMPILAP-PVPEPSVTPLEVSRTSSTIEISFRQGY-----------FSNAHGMVRSYTIIIAEDV 1150
            :.|:..| .:|.|..||..||.|.|  |.:....|           .|.....|||...|.
pombe   171 SFPLRVPINIPPPLCTPSVVSDTFS--EFASHAEYPGFSGLTPFSIHSPTASSVRSCQSIY---- 229

  Fly  1151 GKNASGLEMPSWQDVQAYTVWLPYQAIEPYNPFLTSNGSRKSSLEAE--HFTIGTANCDKHQAGY 1213
               .|.|..|:    .|:...:||   .|.:|.::...|..|:.:.:  .|.:|.|    .|...
pombe   230 ---GSPLSPPN----SAFQAEMPY---FPISPAISCASSCPSTPDEQKNFFIVGNA----PQQTP 280

  Fly  1214 CNGPLRAGTTY----------RIKIRAFTDEDKFTDTVYSSPITTERSDTVIV------------ 1256
            ....||:..:|          ..::|:|::..|.::.|  :|..::.|..:|.
pombe   281 ARPSLRSVPSYPSSNNQRRPSASRVRSFSNYVKSSNVV--NPSLSQASLEIIPRKSMKRDSNAQN 343

  Fly  1257 --AATVSAVLLVAMVLVVVYCQHRCQLIRRASKLARMQDELAALPEGYITPNRPVHVKD-----F 1314
              .:|:::.|                  :.:..|:..:|  |..|.|....|:|...|:     |
pombe   344 DGTSTMTSKL------------------KPSVGLSNTRD--APKPGGLRRANKPCFNKETKGSIF 388

  Fly  1315 SEHYR-----------------------IMSADSDFRFS--EEFEELKHVG-RDQACSFANLPCN 1353
            |:..:                       :.:|...::|.  ||.|..:.:. .|....:..|..:
pombe   389 SKENKGPFTCNPWGAKKVSPPPCEVLADLNTASIFYKFKRLEEMEMTRSLAFNDSKSDWCCLASS 453

  Fly  1354 RP-----KNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFW 1413
            |.     |||:|:|:|||.:|.:|  ......||||||:::...|  :::|..|.|...|..:||
pombe   454 RSTSISRKNRYTDIVPYDKTRVRL--AVPKGCSDYINASHIDVGN--KKYIACQAPKPGTLLDFW 514

  Fly  1414 RMCWESN--SRAIVMLTRCFEKGREKCDQYWP--VDRVAMFYGDIKV---------QLIIDTHYH 1465
            .|.|.::  :..|||||..:|.|.|||.||||  .|......|.:::         .|.::||.
pombe   515 EMVWHNSGTNGVIVMLTNLYEAGSEKCSQYWPDNKDHALCLEGGLRISVQKYETFEDLKVNTHL- 578

  Fly  1466 DWSISEFMVSR-NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVHCSAGV 1529
                  |.:.: |...:.:.||...||.|...|: .:|:...:|.. |.:..| .|:.|||||||
pombe   579 ------FRLDKPNGPPKYIHHFWVHTWFDKTHPD-IESITGIIRCI-DKVPND-GPMFVHCSAGV 634

  Fly  1530 GRSGTFIALDRILQHIHKS---------DYVD-IFGIVFAMRKERVFMVQTEQQY 1574
            ||:|||||:|:||| :.|:         |..| ||..|.::|.:|:.|||..:|:
pombe   635 GRTGTFIAVDQILQ-VPKNILPKTTNLEDSKDFIFNCVNSLRSQRMKMVQNFEQF 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp4E	NP_001162669.1	FN3	151..242	CDD:238020
		fn3	247..328	CDD:278470
		fn3	343..417	CDD:278470
		fn3	443..525	CDD:278470
		FN3	548..611	CDD:238020
		FN3	620..706	CDD:238020
		fn3	708..796	CDD:278470
		fn3	824..886	CDD:278470
		fn3	902..978	CDD:278470
		fn3	1013..1092	CDD:278470
		UP_III_II	1106..>1248	CDD:297589	37/164 (23%)
		PTPc	1329..1582	CDD:214550	94/278 (34%)
		PTPc	1355..1582	CDD:238006	87/249 (35%)
pyp2	NP_594899.1	DSP_MapKP	4..129	CDD:238723
		COG5599	405..709	CDD:227886	95/299 (32%)
		PTPc	461..697	CDD:238006	87/243 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3031
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940