Protein Alignment Ptp4E and C17H12.3

DIOPT Version :10

• Sequence 1: NP_525076.2
• Gene: Ptp4E / 31425
• FlyBaseID: FBgn0004368
• Length: 1767
• Species: Drosophila melanogaster
• Sequence 2: NP_001379692.1
• Gene: C17H12.3 / 177443
• WormBaseID: WBGene00015929
• Length: 374
• Species: Caenorhabditis elegans
• Alignment Length: 282
• Identity: 90/282 - (31%)
• Similarity: 143/282 - (50%)
• Gaps: 47/282 - (16%)

  Fly  1328 RFSEEFEEL-KHVGRD------QACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDD------ 1379
            :..:||.:: |:...|      .|...||:  |..|||:.::           |..|.:
 Worm    77 KLRDEFRQMAKYTRPDMTQNAFNANQSANI--NETKNRYADV-----------PCQDQNIVLVAK 128

  Fly  1380 ---GSDYINANYMPGHNSP-REFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQ 1440
               .|||::||::.....| :.||.|||||..|.::||.|..:.....||||.:..|.|:.||.|
 Worm   129 PPAPSDYVHANFVGCPMVPDKRFICTQGPLDHTVDDFWWMIVQQKVEQIVMLCKTIETGKYKCAQ 193

  Fly  1441 YWPVDRVAM-----FYGDIKVQLIIDTHYHD----WSISEFMVSRNCESRIMRHFHFTTWPDFGV 1496
            |||   :||     ..|.|.|:.:..|...|    ..|:...||...:...:||.|::.|||.||
 Worm   194 YWP---LAMGEKKEVKGGIVVENVSGTKPMDRDAEIQITTLQVSFGDQKMSVRHLHWSDWPDRGV 255

  Fly  1497 PEPPQSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYV-DIFGIVFAM 1560
            |....:.:..:.|.|   |:.: ||:||||||:||:||.:|::.||:.|.::... .:..:|.::
 Worm   256 PPCKLTSLELLSAVR---GSRV-PIVVHCSAGIGRTGTIVAIEYILERIAENKQCPPMPDLVKSL 316

  Fly  1561 RKERVFMVQTEQQYVCIHQCLL 1582
            |.:|.:.:||:.||:.||:.:|
 Worm   317 RDQRAYSIQTDMQYLYIHRVML 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp4E	NP_525076.2	FN3	<94..>334	CDD:442628
		fn3	247..328	CDD:394996
		FN3	319..>749	CDD:442628
		fn3	708..796	CDD:394996
		fn3	902..978	CDD:394996
		fn3	1013..1092	CDD:394996
		PTP_tm	1127..1247	CDD:465889
		R3-PTPc	1358..1579	CDD:350396	78/240 (33%)
C17H12.3	NP_001379692.1	PTPc	77..339	CDD:214550	90/282 (32%)