DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp4E and Y48G9A.9

DIOPT Version :9

Sequence 1:	NP_001162669.1	Gene:	Ptp4E / 31425	FlyBaseID:	FBgn0004368	Length:	1767	Species:	Drosophila melanogaster
Sequence 2:	NP_001022893.1	Gene:	Y48G9A.9 / 175343	WormBaseID:	WBGene00021702	Length:	361	Species:	Caenorhabditis elegans

Alignment Length:	309	Identity:	95/309 - (30%)
Similarity:	145/309 - (46%)	Gaps:	54/309 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1302 YITPNRPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYD 1366
            :|.....:.::..::.||.:.|..|  .|..||..|.              |..|||:::::..|
Worm    60 FIIATEKLGIEGLAKQYRKLDAQQD--SSLTFEAFKQ--------------NMHKNRYSDVVCRD 108

  Fly  1367 HSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCF 1431
            .:|.|| .:|.....|||:|||:..:.....||.|||||..|..:||||.::..:.:|:||.:..
Worm   109 TTRVKL-TIDKSRYEDYIHANYVKTNYLRNTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTM 172

  Fly  1432 EKGREKCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMVSR-----------------NCE 1479
            |:||.||..|||...|...||.|:|     |:..: |..||.:..                 |.:
Worm   173 EEGRPKCVGYWPSLGVTETYGCIRV-----TNMGE-SSDEFEICNLAVTFVPDNVPVDEQPANLK 231

  Fly  1480 SRIMRHFHFTTWPDFGVPEP-----PQSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALD 1539
            ...:....:..|||.|||:.     ||.|:..||         ..|.:||||||:||:|..:||:
Worm   232 ELRVNLIKWPNWPDRGVPDEKCHTVPQRLLAQVR---------HGPCVVHCSAGIGRTGCVVALE 287

  Fly  1540 RILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGK 1588
            .....:.:...||...|:..:||:|...:|||.||:.||:.::|...|:
Worm   288 FAYNKLDRGLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARGE 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp4E	NP_001162669.1	FN3	151..242	CDD:238020
		fn3	247..328	CDD:278470
		fn3	343..417	CDD:278470
		fn3	443..525	CDD:278470
		FN3	548..611	CDD:238020
		FN3	620..706	CDD:238020
		fn3	708..796	CDD:278470
		fn3	824..886	CDD:278470
		fn3	902..978	CDD:278470
		fn3	1013..1092	CDD:278470
		UP_III_II	1106..>1248	CDD:297589
		PTPc	1329..1582	CDD:214550	88/274 (32%)
		PTPc	1355..1582	CDD:238006	83/248 (33%)
Y48G9A.9	NP_001022893.1	PTPc	71..330	CDD:214550	92/290 (32%)
Y48G9A.9	NP_001022893.1	PTPc	97..330	CDD:238006	83/248 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910