DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptp4E and XB22169588

DIOPT Version :9

Sequence 1:	NP_001162669.1	Gene:	Ptp4E / 31425	FlyBaseID:	FBgn0004368	Length:	1767	Species:	Drosophila melanogaster
Sequence 2:	XP_002933047.2	Gene:	XB22169588 / 100493594	XenbaseID:	XB-GENE-22169589	Length:	301	Species:	Xenopus tropicalis

Alignment Length:	283	Identity:	129/283 - (45%)
Similarity:	173/283 - (61%)	Gaps:	8/283 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly  1306 NRPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRF 1370
            :|.:.|..|.|.:.:...|.:..|.:||:||..||.||:...|..|.|..|||:.:||||||::.
Frog     7 SRAMPVCSFQEMFYMKQKDENNIFIKEFKELTDVGNDQSKEAAETPANAMKNRYAHILPYDHTQV 71

  Fly  1371 KLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGR 1435
            ||..:|.:..|.||||||:||....:|:|.||.||.:|..:||||.||...|.|||||.|.|:|:
Frog    72 KLSLIDGNLDSGYINANYIPGFGDGKEYIATQAPLPATFVDFWRMIWEQRVRIIVMLTVCEEQGK 136

  Fly  1436 EKCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMVSR----NCESRIMRHFHFTTWPDFGV 1496
            ..||||||.|.|:  ||.|.|..:.:.|..||:|..|.:.:    :..:|.:...|:|||||.||
Frog   137 VLCDQYWPADTVS--YGLIAVHKVSELHSKDWTIRHFTIQKINNADTSARSIYQLHYTTWPDRGV 199

  Fly  1497 PEPPQSLVRFVRAFRDVIGT--DMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFA 1559
            |..|.|||.||...|:.:..  |..|.::||||||||:|||||||..||.::....:|||..|..
Frog   200 PINPVSLVTFVEFVREHVQAVKDSGPTVLHCSAGVGRTGTFIALDVALQQLNAGQCIDIFQTVHK 264

  Fly  1560 MRKERVFMVQTEQQYVCIHQCLL 1582
            ||..|..|:|||:||:.:|.|:|
Frog   265 MRLSRYLMLQTEEQYIFVHYCIL 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptp4E	NP_001162669.1	FN3	151..242	CDD:238020
		fn3	247..328	CDD:278470
		fn3	343..417	CDD:278470
		fn3	443..525	CDD:278470
		FN3	548..611	CDD:238020
		FN3	620..706	CDD:238020
		fn3	708..796	CDD:278470
		fn3	824..886	CDD:278470
		fn3	902..978	CDD:278470
		fn3	1013..1092	CDD:278470
		UP_III_II	1106..>1248	CDD:297589
		PTPc	1329..1582	CDD:214550	123/258 (48%)
		PTPc	1355..1582	CDD:238006	111/232 (48%)
XB22169588	XP_002933047.2	PTPc	30..288	CDD:214550	124/260 (48%)
XB22169588	XP_002933047.2	PTPc	57..288	CDD:238006	112/233 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D16347at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010