Protein Alignment CG6903 and Hgsnat

DIOPT Version :9

• Sequence 1: NP_001284872.1
• Gene: CG6903 / 31423
• FlyBaseID: FBgn0029737
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_084160.1
• Gene: Hgsnat / 52120
• MGIID: 1196297
• Length: 656
• Species: Mus musculus
• Alignment Length: 601
• Identity: 213/601 - (35%)
• Similarity: 322/601 - (53%)
• Gaps: 60/601 - (9%)

  Fly    20 LSVDEFYLYLRSE-FSSQTHLYSLSDECYTCPYTKVKALPAADV------AAVVVEPLRLSSAYS 77
            |.:|:..|.:.:| ..:...:|..||:||.|.:.     |.|:|      |...|.|:.:|:.:.
Mouse    72 LKMDQALLLIHNELLGTSLTVYWKSDDCYQCTFQ-----PLANVSHGGKPAKPSVAPVSVSTQHG 131

  Fly    78 LNFKIFDLDQGHYAYDNVSSLCWLRRSDLQEFGVYNLTLQ--ANGTCAFAVD--------KPGVP 132
            ...::....:...|       |.|... ..|||.|:|.:|  ::|....|.|        ...:|
Mouse   132 SILQVNSTSEERAA-------CRLEYK-FGEFGNYSLLVQHASSGANKIACDIIVNENPVDSNLP 188

  Fly   133 INYAF---IAVFVLVAALLIALKL------VSCAWRYYRYDE-------ATAAADSIG---EAAT 178
            ::.||   :|:.|.|:.|.:.|.|      :|........|.       :.:.||.:.   :..|
Mouse   189 VSIAFLVGLALIVAVSLLRLLLSLDDVNNWISKTIASRETDRLINSELGSPSRADPLSADYQPET 253

  Fly   179 KATQRKRLRSLDTFRGISIVLMIFVNSGGGGYAWIEHAAWNGLHLADVVFPSFLWIMGVCIPLSV 243
            :.:...|||.:|||||:::|||:|||.|||.|.:.:|::||||.:||:|||.|::|||..|.||:
Mouse   254 RRSSANRLRCVDTFRGLALVLMVFVNYGGGKYWYFKHSSWNGLTVADLVFPWFVFIMGTSIFLSM 318

  Fly   244 KSQLSRGSSKARICLRILWRSIKLFVIGLCL---NSMSGP-NLEQLRIMGVLQRFGVAYLVVAIL 304
            .|.|.||.||.::..:|:|||..|..||:.:   |...|| :.:::||.|||||.||.|.|||:|
Mouse   319 TSILQRGCSKLKLLGKIVWRSFLLICIGVIIVNPNYCLGPLSWDKVRIPGVLQRLGVTYFVVAVL 383

  Fly   305 HTLCCRREPIS-PQRSWQRAVHDVCLFSGELAVLLALVATYLGLTFGLRVPGCPRGYLGPGGKHD 368
            .....:..|.| ...|...::.|:.....:...:|.|.:.:|.|||.|.|||||.|||||||..|
Mouse   384 EFFFWKPVPDSCTLESSCFSLRDITSSWPQWLTILTLESIWLALTFFLPVPGCPTGYLGPGGIGD 448

  Fly   369 YNAHPKCIGGAAGYADLQVLGNAHIYQHPTAKYVYDS-TAFDPEGIFGCILSVVQVLLGAFAGVT 432
            ...:|.|.||||||.|..:||:.|:||||::..:|.: .|:||||:.|.|.|:|...||..|| .
Mouse   449 LGKYPHCTGGAAGYIDRLLLGDNHLYQHPSSTVLYHTEVAYDPEGVLGTINSIVMAFLGVQAG-K 512

  Fly   433 LLVHPNFQSR--IRRWTLLAILLGLIGGALCGFSREGGAIPMNKNLWSLSFVCVTVSLALLILSL 495
            :||:...|::  :.|:.....:||||...|...|...|.||:||||||:|:|......|..||.:
Mouse   513 ILVYYKDQTKAILTRFAAWCCILGLISIVLTKVSANEGFIPINKNLWSISYVTTLSCFAFFILLI 577

  Fly   496 MYYFIDVRETWSWSGYPFTECGMNAIVMYVGHSVLHKMLPWHWRIGEMNTHFMLLLEATWNTLVW 560
            :|..:||:..  |:|.||...|||:|::||||.||....|:.|::.:..:|...|::....|.:|
Mouse   578 LYPVVDVKGL--WTGTPFFYPGMNSILVYVGHEVLENYFPFQWKLADEQSHKEHLIQNIVATALW 640

  Fly   561 VGIALYLDAQEFYYSV 576
            |.||..|..::.::.:
Mouse   641 VLIAYVLYKKKLFWKI 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6903	NP_001284872.1	DUF418	185..542	CDD:304389	162/364 (45%)
Hgsnat	NP_084160.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..253		2/18 (11%)
		DUF418	258..656	CDD:304389	170/400 (43%)
		Lysosomal targeting region. /evidence=ECO:0000250	641..656		4/14 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844431
Domainoid	1	1.000	190	1.000	Domainoid score	I3275
eggNOG	1	0.900	-	-		E1_COG4299
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15586
Inparanoid	1	1.050	312	1.000	Inparanoid score	I2563
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004688
OrthoInspector	1	1.000	-	-		oto94051
orthoMCL	1	0.900	-	-		OOG6_103546
Panther	1	1.100	-	-	LDO	PTHR31061
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5848
SonicParanoid	1	1.000	-	-		X3874
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.780