Protein Alignment CG6903 and HGSNAT

DIOPT Version :9

• Sequence 1: NP_001284872.1
• Gene: CG6903 / 31423
• FlyBaseID: FBgn0029737
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_005273466.1
• Gene: HGSNAT / 138050
• HGNCID: 26527
• Length: 672
• Species: Homo sapiens
• Alignment Length: 654
• Identity: 228/654 - (34%)
• Similarity: 331/654 - (50%)
• Gaps: 112/654 - (17%)

  Fly    11 KWRHLDMRALSVDEFYLYLRSEFS-SQTHLYSLSDECYTC--------PYTKVKALPAADVAAVV 66
            |.||.:   |.:|:..|.:.:|.. :...:|..|:.||.|        |.:.....|:|..|:|.
Human    43 KKRHAE---LKMDQALLLIHNELLWTNLTVYWKSECCYHCLFQVLVNVPQSPKAGKPSAAAASVS 104

  Fly    67 VEPLRLSSAYSLNFKIFDLDQGHYAYDNVSSLCWLRRSDLQEFGVYNLTLQ--ANG----TCAFA 125
            .:.   .|...||..:.:           ..:|.|... ..|||.|:|.::  .||    .|..|
Human   105 TQH---GSILQLNDTLEE-----------KEVCRLEYR-FGEFGNYSLLVKNIHNGVSEIACDLA 154

  Fly   126 VDKPGV----PINYAF---IAVFVLVAALLIALKL------VSCAWRYYRYDE-------ATAAA 170
            |::..|    |::.||   :||.::::.|.:.|.|      :|.|......|.       :.:..
Human   155 VNEDPVDSNLPVSIAFLIGLAVIIVISFLRLLLSLDDFNNWISKAISSRETDRLINSELGSPSRT 219

  Fly   171 DSIGEAATKATQR-----KRLRSLDTFRGISIVLMIFVNSGGGGYAWIEHAAWNGLHLADVVFPS 230
            |.:......||.|     .||||:||||||:::||:|||.|||.|.:.:||:||||.:||:|||.
Human   220 DPLDGDVQPATWRLSALPPRLRSVDTFRGIALILMVFVNYGGGKYWYFKHASWNGLTVADLVFPW 284

  Fly   231 FLWIMGVCIPLSVKSQLSRGSSKARICLRILWRSIKLFVIGLCL---NSMSGP-NLEQLRIMGVL 291
            |::|||..|.||:.|.|.||.||.|:..:|.|||..|..||:.:   |...|| :.:::||.|||
Human   285 FVFIMGSSIFLSMTSILQRGCSKFRLLGKIAWRSFLLICIGIIIVNPNYCLGPLSWDKVRIPGVL 349

  Fly   292 QRFGVAYLVVAILHTLCCRREP--ISPQRSWQRAVHDVCLFSGELAVLLALVATYLGLTFGLRVP 354
            ||.||.|.|||:|..|..:..|  .:.:||. .::.|:.....:..::|.|...:|||||.|.||
Human   350 QRLGVTYFVVAVLELLFAKPVPEHCASERSC-LSLRDITSSWPQWLLILVLEGLWLGLTFLLPVP 413

  Fly   355 GCPRGYLGPGGKHDYNAHPKCIGGAAGYADLQVLGNAHIYQHPTAKYVYDS-TAFDPEGIFGCIL 418
            |||.|||||||..|:..:|.|.||||||.|..:||:.|:||||::..:|.: .|:|||||.|.|.
Human   414 GCPTGYLGPGGIGDFGKYPNCTGGAAGYIDRLLLGDDHLYQHPSSAVLYHTEVAYDPEGILGTIN 478

  Fly   419 SVVQVLLG-------------------------------------AFAGVTLLVHPNFQSRIR-- 444
            |:|...||                                     |.||..||.   :::|.:
Human   479 SIVMAFLGVQCCPDWVTKQACLTEPLSPLWRILFGPCLEVRATEPAQAGKILLY---YKARTKDI 540

  Fly   445 --RWTLLAILLGLIGGALCGFSREGGAIPMNKNLWSLSFVCVTVSLALLILSLMYYFIDVRETWS 507
              |:|....:||||..||...|...|.||:||||||||:|....|.|..||.::|..:||:..
Human   541 LIRFTAWCCILGLISVALTKVSENEGFIPVNKNLWSLSYVTTLSSFAFFILLVLYPVVDVKGL-- 603

  Fly   508 WSGYPFTECGMNAIVMYVGHSVLHKMLPWHWRIGEMNTHFMLLLEATWNTLVWVGIALYLDAQEF 572
            |:|.||...|||:|::||||.|.....|:.|::.:..:|...|.:....|.:||.||..|..::.
Human   604 WTGTPFFYPGMNSILVYVGHEVFENYFPFQWKLKDNQSHKEHLTQNIVATALWVLIAYILYRKKI 668

  Fly   573 YYSV 576
            ::.:
Human   669 FWKI 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6903	NP_001284872.1	DUF418	185..542	CDD:304389	172/404 (43%)
HGSNAT	XP_005273466.1	DUF418	239..672	CDD:304389	180/438 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154189
Domainoid	1	1.000	196	1.000	Domainoid score	I3143
eggNOG	1	0.900	-	-		E1_COG4299
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15586
Inparanoid	1	1.050	319	1.000	Inparanoid score	I2541
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1028480at2759
OrthoFinder	1	1.000	-	-		FOG0004688
OrthoInspector	1	1.000	-	-		oto90466
orthoMCL	1	0.900	-	-		OOG6_103546
Panther	1	1.100	-	-	LDO	PTHR31061
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5848
SonicParanoid	1	1.000	-	-		X3874
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.790