Protein Alignment CG4041 and CG12241

DIOPT Version :10

• Sequence 1: NP_572197.4
• Gene: CG4041 / 31422
• FlyBaseID: FBgn0029736
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 147/688 - (21%)
• Similarity: 230/688 - (33%)
• Gaps: 252/688 - (36%)

  Fly   226 HERYVQMDQRLRQL----LESCLSVLPKRRPLPGELLEHPIFEEVLL--DLKKQKMQPLSPETEH 284
            ||.||..::..|:|    .|..|..||            |:.||:.:  .|:.....|.|..|.
  Fly    12 HEGYVGREEHTRKLQNLGSEDDLGELP------------PMMEELSVADGLRPNPGGPFSALTA- 63

  Fly   285 LPLLLRCPLSQIYHLW------QLAGGDVQAEL--------------------KKEGLIRSEAPI 323
                         .:|      :|.||   |||                    :::|..:|...:
  Fly    64 -------------SMWPQEILAKLGGG---AELASGPNDQPEYRFDEFGFRVEEEDGPEQSSNKL 112

  Fly   324 LGLPQIVRLSGASVCPGRSQAQLMDDRVVPLRLKALLQRLSGLPAAVYFPLLHSPRFPAH--FAR 386
            |.:|.:            ..||               |||..:               ||  |:.
  Fly   113 LSIPFV------------EDAQ---------------QRLQWI---------------AHLEFSH 135

  Fly   387 ELQELPLVIREKDIEY-QFQRVRLFARLLQGYPHTAEQLQREAAVDVPPLLRGPIWAALLEVVPN 450
            ..:...|.....|:.. :.:::|...|  ||.|||               ||..:|..|     :
  Fly   136 NKEAAELSWEHVDVMLPRTEKLRNMVR--QGIPHT---------------LRAQMWMRL-----S 178

  Fly   451 GSYAKIDKFTSTS--------------TDRQIEVDIPRCHQYDELLSSPDGH--RKLRRLLK--A 497
            |:.||..| :.||              |.:|||.|:.|....:...|:|:|.  .:|||:|:  |
  Fly   179 GALAKKQK-SETSYHDIVKASSNDQLMTSKQIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIA 242

  Fly   498 WVTAHPQYVYWQGLDSLTAPFLYLNFNNEELAFLSLFKFIPKYLQWFFLKDN-----------SA 551
            |:  .|...|.||...:.|..|.  |..||.||..:...:...|...:....           ..
  Fly   243 WL--FPDIGYCQGTGVIVACLLL--FMEEENAFWMMATIVEDLLPASYYSSTLLGIQADQRVMHT 303

  Fly   552 VIKEYLSKFSQLTAFHEPLLAQHLASISFIPELFAIPWFLTMFSHVFPLHKILHLWDKLMLGDSS 616
            :|..|||...:....|:..|:           |..:.||||:|::|..:..::.:||
  Fly   304 LIANYLSSVDESLRKHDIELS-----------LITLHWFLTLFANVVHMKILVRIWD-------- 349

  Fly   617 YPLFIGIAILRQLRSTLL-------------TSGFNECILLFSDLPDIVMDGCVLESQKMYEATP 668
            :..:.|..:|.||...:|             ...||.    .||:|..|.|..||..|.:.....
  Fly   350 WFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNS----LSDIPGEVTDVEVLFRQALEVGGS 410

  Fly   669 KSIT-----HRQHALRLQPPQALDIGVADVELKHLQQEQCPRISAKDVQFLLD--------NSPA 720
            .|.|     .|:|...|...|...||..:. ..:|.::|..|...:..:.:|:        |...
  Fly   411 LSQTVIDTHRRRHLAYLMADQGHQIGNPEA-APNLPKQQLARRQVRKSKSILEAFLFRGDGNEGD 474

  Fly   721 EL---------ALIDLR-SVVEFGRVHVPHSINIPFATVQLGEQRLEALQVPQLEAQLRGKIVVC 775
            :|         .|:||| ::::.||    |.|.|                    |.:|.|.|.:.
  Fly   475 QLKNKNIRQTEILVDLREAILKVGR----HFITI--------------------EPKLAGHIQLT 515

  Fly   776 VS-NIHQHSVEFSHFLVACGVQRTCILHKGFNVLHSIE 812
            .: :...|:.:..:|:   .|.||  ..:....||..|
  Fly   516 ANYSTESHAKDHENFI---NVART--RKRRAKALHDFE 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4041	NP_572197.4	Protein Kinases, catalytic domain	48..263	CDD:473864	11/40 (28%)
		TBC	432..634	CDD:214540	56/230 (24%)
		RHOD_Kc	706..810	CDD:238783	22/122 (18%)
CG12241	NP_650432.1	TBC	161..375	CDD:214540	63/259 (24%)
		SH3_SGSM3	540..592	CDD:212747	3/9 (33%)
		RUN_SGSM3	570..783	CDD:439050