DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4041 and Tbc1d15-17

DIOPT Version :9

Sequence 1:	NP_572197.4	Gene:	CG4041 / 31422	FlyBaseID:	FBgn0029736	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	NP_001259806.1	Gene:	Tbc1d15-17 / 33184	FlyBaseID:	FBgn0031233	Length:	715	Species:	Drosophila melanogaster

Alignment Length:	369	Identity:	77/369 - (20%)
Similarity:	125/369 - (33%)	Gaps:	76/369 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   412 RLLQGYPHTAEQLQREAAVD-----------------VPPLLRGPIWAALL----------EVVP 449
            |:.:|:|.|..|.......|                 |...||..:|..||          |.:.
  Fly   336 RVERGHPLTETQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIE 400

  Fly   450 NGSYAKIDKF-------TSTSTDR-----------QIEVDIPRCHQYDELLSSPDGHR--KLRRL 494
            ......|:.:       ..|:|..           |||.|:.|..:..:..:..|...  .|:.:
  Fly   401 RRKQKSIEYYNMKAQWLAMTTTQEANFCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGI 465

  Fly   495 LKAWVTAHPQYVYWQGLDSLTAPFLYLNFNNEELAFLSLFKFIPKYLQWFFLKDNSAVIKEYLSK 559
            |..:|..:....|.||:..|.||.|.:..|..: .|.....|:......|.:  :.|.:|...::
  Fly   466 LMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVD-TFWCFVGFMELVFTNFDI--DQAGMKTQFAQ 527

  Fly   560 FSQLTAFHEPLLAQHLASISFIPELFAIPWFLTMFSHVFPLHKILHLWDKL--MLGDSSYPLFIG 622
            ..:|..|....|..::.|.......|...|.|..:........:|.||:.|  .|...::.|...
  Fly   528 IRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFHLLFS 592

  Fly   623 IAILRQLRSTLLTS--GFNECILLFSDLP---DI-----VMDGCVLESQKMYEATPKSITH--RQ 675
            :|||.|....::.|  .|.|.:...::|.   |:     |.:|..|: .|..|..|..|..  .:
  Fly   593 VAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQ-LKGSETLPNDIRSIIGE 656

  Fly   676 HALRLQPPQALDIGVADVE-----------LKHLQQEQCPRISA 708
            ..|.....:.:|.|:.|.|           :|.|..|:..|..|
  Fly   657 PLLPAAAGEEIDGGMVDEEPTYSDDGFDELVKELTPEEKVRQQA 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4041	NP_572197.4	PKc_like	45..272	CDD:304357
		TBC	432..634	CDD:214540	49/233 (21%)
		RHOD_Kc	706..810	CDD:238783	1/3 (33%)
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931
Tbc1d15-17	NP_001259806.1	TBC	369..598	CDD:214540	48/231 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456515
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940