Protein Alignment CG4041 and Tbck

DIOPT Version :9

• Sequence 1: NP_572197.4
• Gene: CG4041 / 31422
• FlyBaseID: FBgn0029736
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: XP_008759718.1
• Gene: Tbck / 295446
• RGDID: 1307816
• Length: 894
• Species: Rattus norvegicus
• Alignment Length: 900
• Identity: 387/900 - (43%)
• Similarity: 518/900 - (57%)
• Gaps: 105/900 - (11%)

  Fly     8 RECRLCAVTFFAKLHPGDVCGSNGLPLTPNSIAILGRAQKLKELQDEHLCQYLDVIRGKHERTIV 72
            ::..:.|.||||...|.|||||||||||||||.||||.|.||.:....||||:|:.||||||.:|
  Rat     5 KDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQVLKTITHPRLCQYVDISRGKHERLVV 69

  Fly    73 VSEYLGLSLEDYAMRHPPLAIAQILRIFYQVACGINVLSRHHLVAHNVEPKHILLSSDGQRVKLF 137
            |:|:...||||......|.:.:.:|.|.|:|..|:..|::|.:|...:.|.:|||...| .:||.
  Rat    70 VAEHCERSLEDLLRERRPASHSAVLCIAYEVLEGLQYLNKHGIVHRALSPHNILLDRKG-HIKLA 133

  Fly   138 NYGLHHMTKGGAYVPFPIGNIRYMAPERLL--------------GLNGNVKSDVWSLALVMVELI 188
            .:||:|||..|..|.||||...|:|||.:.              .|....|||||||.:::.||.
  Rat   134 KFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIFKSTDHVPSEKPLPSGPKSDVWSLGIILFELC 198

  Fly   189 LQIELWPKLKLSNVVRKILAFGKSNGALEKIAREHQCHERYVQMDQRLRQLLESCLSVLPKRRPL 253
            :..:|:..|.:|..::.:|..|..:..|..:|.||.|.:...::.:....:|:.||:..|.:||.
  Rat   199 VGRKLFQSLDISERLKFLLTLGCVDDTLIVLAEEHGCLDIIKELPENALSILKKCLTFHPPKRPT 263

  Fly   254 PGELLEHPIFEEVLLDLKKQKMQPL-SPETEHLPLL---LRC----------------------- 291
            |.||::..:|.||         .|| :|..:...|.   |||
  Rat   264 PDELMKDQVFSEV---------SPLYTPFIKPASLFSSSLRCADLTLPEDISDVCKDIDDDYLAE 319

  Fly   292 -PLSQIYHLWQLAGGDVQAELKKEGLIRSEAPILGLPQIVRLSGASVCPGRSQAQLMDDRVVPLR 355
             .:.::|:||.|||||::.||..:.:|||:.||..||..:...|.|...||.::.|:||..|.|.
  Rat   320 RSIEEVYYLWCLAGGDLEKELINKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLS 384

  Fly   356 LKALLQRLSGLPAAVYFPLLHSPRFPAHFARELQE------LPLVIREKDIEYQFQRVRLFARLL 414
            |..|..||..:....::|||...:.....:....|      |||:|||:|.|||..|:.||.|||
  Rat   385 LCQLRNRLKDVGGEAFYPLLEDDQSSLPHSNSNNELSAAASLPLIIRERDTEYQLNRIILFDRLL 449

  Fly   415 QGYPHTAEQLQREAAVDVPPLLRGPIWAALL--EVVPNGSYAKIDKFTSTSTDRQIEVDIPRCHQ 477
            :.||:...|:.:||.||:|||:||..|||||  |...:..|..|||.|...||||||||||||||
  Rat   450 KAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQ 514

  Fly   478 YDELLSSPDGHRKLRRLLKAWVTAHPQYVYWQGLDSLTAPFLYLNFNNEELAFLSLFKFIPKYLQ 542
            ||||||||:||.|.||:|||||.:||..|||||||||.|||||||||||.||:..:..||||||.
  Rat   515 YDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLY 579

  Fly   543 WFFLKDNSAVIKEYLSKFSQLTAFHEPLLAQHLASISFIPELFAIPWFLTMFSHVFPLHKILHLW 607
            .|||||||.||:|||:.|||:.:||:|.|:.||..|.|||:|:|||||||||:||||||||.|||
  Rat   580 NFFLKDNSHVIQEYLTVFSQMISFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLW 644

  Fly   608 DKLMLGDSSYPLFIGIAILRQLRSTLLTSGFNECILLFSDLPDIVMDGCVLESQKMYEATPKSIT 672
            |.|:||:||:|..||:|||:|||..||.:|||||||||||||:|.::.||.||..::..||||.|
  Rat   645 DTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESVNLFCWTPKSAT 709

  Fly   673 HRQHALRLQPPQ------------------------ALDIGVADVELKHLQQEQCPRISAKDVQF 713
            :||||   |||:                        ..|:....:.|..|:.|..|||||:|:..
  Rat   710 YRQHA---QPPRPASESSAVRSSSAPYFSAECTDPPKTDLSRESIPLSDLKSEVSPRISAEDLID 771

  Fly   714 LLD---------------NSPAELALIDLRSVVEFGRVHVPHSINIPFATVQLGEQRLEALQVPQ 763
            |.:               :|..:|.::|:|:..:|.|.|:..||||||:.....|..|.......
  Rat   772 LCELTVTGHFKTPTKKTKSSKPKLLVVDIRNSEDFLRGHIAGSINIPFSAAFTAEGELSQGPYTT 836

  Fly   764 LEAQLRGKIVVCVSNIHQHSVEFSHFLVACGVQRTCILHKGFNVLHSIEPNILIS 818
            :....:||::|.|.::.:.:.||:..||.....|.|||..|.|   .|:|..|::
  Rat   837 MLHSFKGKVIVIVGHVAKQTSEFAAHLVKMKYPRVCILDGGIN---KIKPTGLLT 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4041	NP_572197.4	PKc_like	45..272	CDD:304357	84/240 (35%)
		TBC	432..634	CDD:214540	139/203 (68%)
		RHOD_Kc	706..810	CDD:238783	34/118 (29%)
Tbck	XP_008759718.1	S_TKc	43..273	CDD:214567	81/230 (35%)
		PKc_like	43..269	CDD:304357	81/226 (36%)
		TBC	467..671	CDD:214540	139/203 (68%)
		RHOD	772..883	CDD:294087	31/113 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353670
Domainoid	1	1.000	285	1.000	Domainoid score	I1549
eggNOG	1	0.900	-	-		E1_KOG1093
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13221
Inparanoid	1	1.050	670	1.000	Inparanoid score	I708
OMA	1	1.010	-	-		QHG55921
OrthoDB	1	1.010	-	-		D135294at33208
OrthoFinder	1	1.000	-	-		FOG0006493
OrthoInspector	1	1.000	-	-		oto97909
orthoMCL	1	0.900	-	-		OOG6_104373
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5470
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770