Protein Alignment CG4041 and LOC1271672

DIOPT Version :10

• Sequence 1: NP_572197.4
• Gene: CG4041 / 31422
• FlyBaseID: FBgn0029736
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: XP_061509014.1
• Gene: LOC1271672 / 1271672
• VectorBaseID: AGAMI1_004009
• Length: 905
• Species: Anopheles gambiae
• Alignment Length: 859
• Identity: 478/859 - (55%)
• Similarity: 586/859 - (68%)
• Gaps: 71/859 - (8%)

  Fly    11 RLCAVTFFAKLHPGD-VCGSNGLPLTPNSIAILGRAQKLKE--LQDEHLCQYLDVIRGKHERTIV 72
            |:..:|||||.||.| .||:||||||||||.|.||||.||.  |:.||||.|||.|||||||||:
Mosquito    43 RVSVLTFFAKAHPNDECCGTNGLPLTPNSIGIFGRAQLLKSDALRHEHLCTYLDAIRGKHERTII 107

  Fly    73 VSEYLGLSLEDYAMRHPPLA---IAQ------ILRIFYQVACGINVLSRHHLVAHNVEPKHILLS 128
            |.||:|.          |||   |.:      :|||.|||...:..|:|..||..|::|..:|:|
Mosquito   108 VQEYVGC----------PLAETFIGENNKQETLLRIGYQVLAALAHLNRCGLVCRNLDPTSVLVS 162

  Fly   129 SD-GQRVKLFNYGLHHMTKGGAYVPFPIGNIRYMAPERLLGLNGNVKSDVWSLALVMVELILQIE 192
            .| |  |||:||||:|||.||.||.|||||:||.|||.|||...|.|||||||.:|:.||.|...
Mosquito   163 RDFG--VKLYNYGLYHMTGGGRYVSFPIGNVRYQAPEVLLGSRANAKSDVWSLGIVLAELALGCT 225

  Fly   193 LWPKLKLSNVVRKILAFGKSNGAL-EKIAREHQCHERYVQMDQRLRQLLESCLSVLPKRRPLPGE 256
            ||..||||.:|||:|:...:..|: ||:||||...|.|..||..||:::|.||::.|:||||..|
Mosquito   226 LWESLKLSQIVRKVLSLVNTQHAVFEKLAREHNRLEVYEAMDAGLRRIIEECLTISPRRRPLAKE 290

  Fly   257 LLEHPIFEEVLLDLKKQKMQPLSPE----------TEHLPLLLRCPLSQIYHLWQLAGGDVQAEL 311
            .||.|:|:.|.|. ......|.|..          .:||      .|||||:||||||||||.||
Mosquito   291 ALEDPVFDFVRLS-SSSSSSPASASDAIGGGQTLVEKHL------SLSQIYYLWQLAGGDVQQEL 348

  Fly   312 KKEGLIRSEAPILGLPQIVRLSGASVCPGRSQAQLMDDRVVPLRLKALLQRLSGLPAAVYFPLLH 376
            ||||||:||||||.||.:|.|:|.|:.|.:||:.|.|.|::.|....||:||||:|...|.||::
Mosquito   349 KKEGLIKSEAPILSLPNLVMLNGRSISPPKSQSVLHDHRIIFLNFGTLLERLSGIPEEDYLPLIY 413

  Fly   377 SPRFPAHFARELQELPLVIREKDIEYQFQRVRLFARLLQGYPHTAEQLQREAAVDVPPLLRGPIW 441
            |.......|.....|||||||:|:.|||.|:.|...||.|||:|.:.|:..||.|:|||.||.:|
Mosquito   414 STDAYLESANFKTVLPLVIRERDMLYQFHRLVLLNTLLHGYPYTHDLLRSFAAKDIPPLCRGQVW 478

  Fly   442 AALLEVVPNGSYAKIDKFTSTSTDRQIEVDIPRCHQYDELLSSPDGHRKLRRLLKAWVTAHPQYV 506
            |.||.|||||:|.::||.:.|.|||||||||||||||:||||:|:||.||:|||||||.||||||
Mosquito   479 ACLLGVVPNGAYERLDKCSPTHTDRQIEVDIPRCHQYNELLSAPEGHAKLKRLLKAWVAAHPQYV 543

  Fly   507 YWQGLDSLTAPFLYLNFNNEELAFLSLFKFIPKYLQWFFLKDNSAVIKEYLSKFSQLTAFHEPLL 571
            ||||||||||||||||||:||.|||||::||||||..||||||||:|||||.||.||..||||.|
Mosquito   544 YWQGLDSLTAPFLYLNFNDEERAFLSLYRFIPKYLHLFFLKDNSAIIKEYLVKFFQLIFFHEPAL 608

  Fly   572 AQHLASISFIPELFAIPWFLTMFSHVFPLHKILHLWDKLMLGDSSYPLFIGIAILRQLRSTLLTS 636
            |.||..|||||||:||||||||||||||||||.||||||:|||:||||||||||||||:.|||.|
Mosquito   609 ANHLHGISFIPELYAIPWFLTMFSHVFPLHKIFHLWDKLILGDNSYPLFIGIAILRQLKGTLLKS 673

  Fly   637 GFNECILLFSDLPDIVMDGCVLESQKMYEATPKSITHRQHAL---------------------RL 680
            ||||||||||||||||::.||.:|:.||:.||||||:|:.||                     .|
Mosquito   674 GFNECILLFSDLPDIVIESCVNDSETMYQFTPKSITYRKFALHEEGPEEFVREAACCCSQISVEL 738

  Fly   681 QP-----PQALDIGVADVELKHLQQEQCPRISAKDVQFLLDNSPAELALIDLRSVVEFGRVHVPH 740
            .|     |.|.|:...:.:|:.:|.|..||||..|:..||.:.||..|::|:||..::.:|.:.:
Mosquito   739 NPSLFFLPLAQDLNYTEEDLREVQAELHPRISVYDLIRLLRDRPASTAILDIRSSPDYRKVAIEN 803

  Fly   741 SINIPFATVQLGEQRLEALQVPQLEAQLRGK--IVVCVSNIHQHSVEFSHFLVACGVQRTCILHK 803
            |||:|||:|.|.|.|||||.||:|||.||..  |.|.||..|:.::.|:.|||..||....:||:
Mosquito   804 SINVPFASVSLKEPRLEALNVPRLEAYLRRHPLITVIVSVSHESAMLFAKFLVDSGVPYVAVLHR 868

  Fly   804 GFNVLHSIEPNILI 817
            ||..::..:..:::
Mosquito   869 GFEAIYRPDDKLIL 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4041	NP_572197.4	Protein Kinases, catalytic domain	48..263	CDD:473864	117/227 (52%)
		TBC	432..634	CDD:214540	160/201 (80%)
		RHOD_Kc	706..810	CDD:238783	48/105 (46%)
LOC1271672	XP_061509014.1	None