Protein Alignment CG4041 and tbck

DIOPT Version :9

• Sequence 1: NP_572197.4
• Gene: CG4041 / 31422
• FlyBaseID: FBgn0029736
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001096213.1
• Gene: tbck / 100124764
• XenbaseID: XB-GENE-994266
• Length: 880
• Species: Xenopus tropicalis
• Alignment Length: 906
• Identity: 392/906 - (43%)
• Similarity: 510/906 - (56%)
• Gaps: 140/906 - (15%)

  Fly     8 RECRLCAVTFFAKLHPGDVCGSNGLPLTPNSIAILGRAQKLKELQDEHLCQYLDVIRGKHERTIV 72
            ::..|.|.||||...|.|||||||||||||||.||||.|.||.:....||||:|:.||||||.:|
 Frog     5 KDAELGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTIVHPRLCQYVDISRGKHERLVV 69

  Fly    73 VSEYLGLSLEDYAMRHPPLAIAQILRIFYQVACGINVLSRHHLVAHNVEPKHILLSSDGQRVKLF 137
            |:|:...|.||......|::.::|.|:.|:|..|:..::||.:|...:.|.:|||..:| ..||.
 Frog    70 VAEHYPKSFEDLLREGTPVSSSKIFRLAYEVLQGLEYMNRHRMVHRALAPHNILLDGEG-HAKLA 133

  Fly   138 NYGLHHMTKGGAYVPFPIGNIRYMAPERLL--------------GLNGNVKSDVWSLALVMVELI 188
            .:||:|:|..||.|.||||...|:|||.:.              .|....|||||||.|::.||.
 Frog   134 KFGLYHITDHGADVDFPIGYPSYLAPEVIAQGIVKPTDPTQCERPLPSGPKSDVWSLGLILFELC 198

  Fly   189 LQIELWPKLKLSNVVRKILAFGKSNGALEKIAREHQCHERYVQMDQRLRQLLESCLSVLPKRRPL 253
            :..:|:..|.:|..::.||..|..:..:..::.||.|.:....:.:....||..||:..|.:||.
 Frog   199 MGRKLFQSLDISEKLKLILTLGCVDDIITVLSEEHGCEDILKSVPENTLALLRKCLTFHPTKRPT 263

  Fly   254 PGELLEHPIFEEVLLDLKKQKMQPLSPETEHLPL---------LLRC------------------ 291
            ..|||...:|.||         .||     :||.         .|||
 Frog   264 SAELLADSVFSEV---------SPL-----YLPFRKPVGLFSSALRCANLILPEDISLLCKDEDS 314

  Fly   292 ------PLSQIYHLWQLAGGDVQAELKKEGLIRSEAPILGLPQIVRLSGASVCPGRSQAQLMDDR 350
                  .:.::||||.|||||::.||..:|:|||:.||..||.::...|.|...||.::.|:||.
 Frog   315 DFLAERSIEEVYHLWCLAGGDLEKELISKGIIRSKPPICTLPNLLLEDGESFGQGRDRSSLLDDT 379

  Fly   351 VVPLRLKALLQRLSGLPAAVYFPLL--------HSPRFPAHFARELQ---ELPLVIREKDIEYQF 404
            .|.|.|..|..||..:|...|:|||        ||..     :.||.   .|||:|||:|.|||.
 Frog   380 TVTLSLCQLRNRLKDVPGEAYYPLLGEDQSNIPHSGS-----SNELSTSATLPLIIRERDTEYQL 439

  Fly   405 QRVRLFARLLQGYPHTAEQLQREAAVDVPPLLRGPIWAALLEVVPNGS----YAKIDKFTSTSTD 465
            .|:.||.|||..||:....:.:||.||:||||||..|||||.|  .|:    |..|||.|...||
 Frog   440 NRIVLFDRLLNAYPYKKNMIWKEARVDIPPLLRGLTWAALLGV--EGAIQEKYDMIDKDTPIPTD 502

  Fly   466 RQIEVDIPRCHQYDELLSSPDGHRKLRRLLKAWVTAHPQYVYWQGLDSLTAPFLYLNFNNEELAF 530
            ||||||||||||||||||||:||.|.||:|||||.:||..|||||||||.|||||||||||.||:
 Frog   503 RQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPNLVYWQGLDSLCAPFLYLNFNNEALAY 567

  Fly   531 LSLFKFIPKYLQWFFLKDNSAVIKEYLSKFSQLTAFHEPLLAQHLASISFIPELFAIPWFLTMFS 595
            ..:..||||||..|||||||.||:|||..|||:.|||:|.|:.||..|.|||:|:|||||||||:
 Frog   568 ACMSAFIPKYLYNFFLKDNSHVIQEYLKVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFT 632

  Fly   596 HVFPLHKILHLWDKLMLGDSSYPLFIGIAILRQLRSTLLTSGFNECILLFSDLPDIVMDGCVLES 660
            ||||||||.||||.|:||::|:|..||:|||:|||..||.:|||||||||||||:|.::.||.||
 Frog   633 HVFPLHKIFHLWDTLLLGNASFPFCIGVAILQQLRVRLLANGFNECILLFSDLPEIDIERCVRES 697

  Fly   661 QKMYEATPKSITHRQHALRLQPPQAL-----------------------DIGVADVELKHLQQEQ 702
            ..::..||||.|:||||   |.|:.:                       |:|...:.:|.|:.|.
 Frog   698 VNLFCWTPKSATYRQHA---QVPKQISESNGVSRTSASFSVDFQESPKTDLGREPINMKELKLEV 759

  Fly   703 CPRISAKDVQFL-------LDNSPA--------ELALIDLRSVVEFGRVHVPHSINIPFATVQLG 752
            .|||||:|:..|       :...|:        :|.::|:|...:|.|.|:|.|||:|..:....
 Frog   760 SPRISAEDLIDLCELTMPSMSRIPSKKTRSIKPKLLVVDIRHSEDFNRGHIPGSINMPSGSAFTT 824

  Fly   753 EQRLEALQVPQLEAQLRGKIVVCVSNIHQHSVEFSHF-------LVACGVQRTCILHKGFN 806
            |:.|............:||::|.|.:..|.:.|...|       |.|||        |.||
 Frog   825 ERDLAPCPASTTLQNFKGKVIVTVGHAAQDASEIIIFTARVVMDLAACG--------KKFN 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4041	NP_572197.4	PKc_like	45..272	CDD:304357	84/240 (35%)
		TBC	432..634	CDD:214540	141/205 (69%)
		RHOD_Kc	706..810	CDD:238783	33/123 (27%)
tbck	NP_001096213.1	PKc_like	41..270	CDD:304357	82/229 (36%)
		S_TKc	43..273	CDD:214567	81/230 (35%)
		TBC	467..671	CDD:214540	141/205 (69%)
		RHOD	791..>857	CDD:294087	18/65 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	282	1.000	Domainoid score	I1638
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H13221
Inparanoid	1	1.050	679	1.000	Inparanoid score	I716
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D135294at33208
OrthoFinder	1	1.000	-	-		FOG0006493
OrthoInspector	1	1.000	-	-		oto104601
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5470
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160