DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32772 and Zscan29

DIOPT Version :9

Sequence 1:	NP_001284870.1	Gene:	CG32772 / 31420	FlyBaseID:	FBgn0052772	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001277748.1	Gene:	Zscan29 / 99334	MGIID:	2139317	Length:	834	Species:	Mus musculus

Alignment Length:	422	Identity:	110/422 - (26%)
Similarity:	160/422 - (37%)	Gaps:	107/422 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRLCF---QTATLFQVPGYSIPTCVRCSEQLTNNSNFHQSAAAAAAVAASAS---AAVAASAAAA 63
            ||..|   ||:......|.::.||....|         ..|..:|.|||..|   .....|....
Mouse   452 CRTKFKSLQTSYRKVKNGQALETCPFFEE---------MDALVSAQVAAPPSDDQEKETVSCCLQ 507

  Fly    64 ATSSSTASSSDSDAIAQQQQH------------------QNPQQ-----QQHQNSQQQQQQQQQM 105
            .||.:.....|.|........                  |:|..     :..:||::...::.|:
Mouse   508 RTSEAEPEKQDEDTEEDSDDEDDTEIPPEAVITRAPVLFQSPSGFEAGFENEENSKRDISEEVQL 572

  Fly   106 -----------------QSSSSSENLQSQDD------SEDVDLIFNEEG-------------SCP 134
                             ||.:|.....|:..      .|...|.|.|:.             ..|
Mouse   573 HRTLLARSERKISHHVNQSKASKNKCSSESQWEKTQREEQRQLAFPEKNIGKVLTYQRPGLEDRP 637

  Fly   135 LCNKTFSRKSSLMTHIR---NHSAERKFVCTYCHKGFTQAANLRNHERIHTNDRPYQCVDCGKTF 196
            .....:.:.|...:|:|   :|..|..:.|..|.|.|:::|.|..|:||||.::||:|:||||.|
Mouse   638 YKYVKYGKSSGSNSHLRYPVSHEVENPYKCADCGKSFSRSARLIRHQRIHTGEKPYKCLDCGKGF 702

  Fly   197 TQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCNKKFTQVTSLN 261
            ...:|...|||:||||:|:.|:  |||:.|.|.::|..|.::|...:.|.|..|.|.|...:..|
Mouse   703 RDSSNFITHRRIHTGEKPYQCD--ECGKRFNQSSSLIIHQRTHTGEKPYQCEECGKSFNNSSHFN 765

  Fly   262 QHLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHGLAFPYECDKCDEKFLQQAHLDQHLKMHDE 326
            .|.:.|.|...:.||.| .|:|...|.||.|.:||....||.|                   ||
Mouse   766 AHRRIHTGERPHVCPDC-GKSFSKSSDLHAHHRTHTGKKPYGC-------------------HD- 809

  Fly   327 FKFKCDICPSSFNQESLLKKHVQRHVEGRYLS 358
                   |...|::.|.|.||.:.|...:.||
Mouse   810 -------CGKCFSKSSALSKHRETHTREKLLS 834

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32772	NP_001284870.1	COG5048	<124..378	CDD:227381	80/251 (32%)
		C2H2 Zn finger	133..153	CDD:275368	4/22 (18%)
		zf-H2C2_2	145..170	CDD:290200	8/27 (30%)
		C2H2 Zn finger	161..181	CDD:275368	8/19 (42%)
		zf-H2C2_2	173..198	CDD:290200	14/24 (58%)
		C2H2 Zn finger	189..209	CDD:275368	10/19 (53%)
		C2H2 Zn finger	217..239	CDD:275368	8/21 (38%)
		zf-H2C2_2	231..256	CDD:290200	8/24 (33%)
		C2H2 Zn finger	247..267	CDD:275368	6/19 (32%)
		C2H2 Zn finger	275..296	CDD:275368	9/20 (45%)
		C2H2 Zn finger	304..324	CDD:275368	1/19 (5%)
		C2H2 Zn finger	331..351	CDD:275368	6/19 (32%)
		C2H2 Zn finger	359..380	CDD:275368	110/422 (26%)
Zscan29	NP_001277748.1	SCAN	13..123	CDD:128708
		SCAN	13..101	CDD:280241
		Myb_DNA-bind_4	238..319	CDD:290549
		Myb_DNA-bind_4	399..480	CDD:290549	8/27 (30%)
		COG5048	<663..823	CDD:227381	66/189 (35%)
		zf-C2H2	665..687	CDD:278523	8/21 (38%)
		C2H2 Zn finger	667..687	CDD:275368	8/19 (42%)
		zf-H2C2_2	680..702	CDD:290200	13/21 (62%)
		C2H2 Zn finger	695..715	CDD:275368	10/19 (53%)
		zf-H2C2_2	707..732	CDD:290200	14/26 (54%)
		C2H2 Zn finger	723..743	CDD:275368	8/21 (38%)
		zf-H2C2_2	735..760	CDD:290200	8/24 (33%)
		C2H2 Zn finger	751..771	CDD:275368	6/19 (32%)
		zf-H2C2_2	763..787	CDD:290200	8/24 (33%)
		zf-C2H2	777..799	CDD:278523	9/22 (41%)
		C2H2 Zn finger	779..799	CDD:275368	9/20 (45%)
		C2H2 Zn finger	807..827	CDD:275368	9/46 (20%)
		zf-C2H2	807..827	CDD:278523	9/46 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100