DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32772 and PGBD1

DIOPT Version :9

Sequence 1:NP_001284870.1 Gene:CG32772 / 31420 FlyBaseID:FBgn0052772 Length:520 Species:Drosophila melanogaster
Sequence 2:NP_001171672.1 Gene:PGBD1 / 84547 HGNCID:19398 Length:809 Species:Homo sapiens


Alignment Length:389 Identity:75/389 - (19%)
Similarity:131/389 - (33%) Gaps:92/389 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 SNFHQSAAAAAAVAASASAAVAASAAAAATSSSTASSSDSDAIAQQQQHQNPQQQQ------HQN 94
            :..|.|:...||...:........|..:......:.|.|||.....:....|.|::      .:.
Human   324 ARMHISSLEYAAGDITRKGRKKDKARVSELLQGLSFSGDSDVEKDNEPEIQPAQKKLKVSCFPEK 388

  Fly    95 SQQQQQQQQQMQSSSSSE----NLQSQ--DDSEDVDLIFNEEGSCPLCNKTFSRKSSLMTHIRNH 153
            |..::..:....|.|:.:    ||:|:  :..|..:|.|::|....:.|:|.:..|.     :|.
Human   389 SWTKRDIKPNFPSWSALDSGLLNLKSEKLNPVELFELFFDDETFNLIVNETNNYASQ-----KNV 448

  Fly   154 SAERKFVCTYCHKGFTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCN 218
            |.|.......|..|....:....|.|   .:..::..|        |:.|..|.....:|     
Human   449 SLEVTVQEMRCVFGVLLLSGFMRHPR---REMYWEVSD--------TDQNLVRDAIRRDR----- 497

  Fly   219 EPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCNKKFTQ----VTSLNQHLQAHAGVTGYYC---P 276
                   |..:.: |.|...:..:.|      ..|||:    :..:|::...:|.:..|||   .
Human   498 -------FELIFS-NLHFADNGHLDQ------KDKFTKLRPLIKQMNKNFLLYAPLEEYYCFDKS 548

  Fly   277 RCP---------EKNFKLQSQLHTHMKTHGLAF---PYECD---KCDEKFLQQAHLDQHLKMH-- 324
            .|.         .|..::..::.....|.|...   ||:.:   |.||.  ....|..:|.|:  
Human   549 MCECFDSDQFLNGKPIRIGYKIWCGTTTQGYLVWFEPYQEESTMKVDED--PDLGLGGNLVMNFA 611

  Fly   325 ----DEFKFKCDICPSSFNQE----SLLKKHVQRHV----EGRYLSCPVANCAESFAVRQHLSK 376
                :..::...:|..||...    |.|||...|..    |.|...||:.|.       :|:.|
Human   612 DVLLERGQYPYHLCFDSFFTSVKLLSALKKKGVRATGTIRENRTEKCPLMNV-------EHMKK 668

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32772NP_001284870.1 COG5048 <124..378 CDD:227381 57/289 (20%)
C2H2 Zn finger 133..153 CDD:275368 3/19 (16%)
zf-H2C2_2 145..170 CDD:290200 5/24 (21%)
C2H2 Zn finger 161..181 CDD:275368 4/19 (21%)
zf-H2C2_2 173..198 CDD:290200 3/24 (13%)
C2H2 Zn finger 189..209 CDD:275368 4/19 (21%)
C2H2 Zn finger 217..239 CDD:275368 3/21 (14%)
zf-H2C2_2 231..256 CDD:290200 5/24 (21%)
C2H2 Zn finger 247..267 CDD:275368 4/23 (17%)
C2H2 Zn finger 275..296 CDD:275368 3/32 (9%)
C2H2 Zn finger 304..324 CDD:275368 5/22 (23%)
C2H2 Zn finger 331..351 CDD:275368 7/23 (30%)
C2H2 Zn finger 359..380 CDD:275368 5/18 (28%)
PGBD1NP_001171672.1 SCAN 40..142 CDD:128708
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 170..199
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 271..297
DDE_Tnp_1_7 418..775 CDD:372752 58/295 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23226
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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