DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32772 and ZNF394

DIOPT Version :9

Sequence 1:NP_001284870.1 Gene:CG32772 / 31420 FlyBaseID:FBgn0052772 Length:520 Species:Drosophila melanogaster
Sequence 2:NP_115540.2 Gene:ZNF394 / 84124 HGNCID:18832 Length:561 Species:Homo sapiens


Alignment Length:335 Identity:99/335 - (29%)
Similarity:155/335 - (46%) Gaps:58/335 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    68 STASSSDSDAIAQQQ------QHQNPQQQQHQNS----------QQQQQQQQQMQSSSSSENL-- 114
            |...|:..|.:.:|.      :.:|..:.:..||          :.:..:..::|:|:...||  
Human   233 SKCGSTHEDRVEKQSGDPLPLKLENSPEAEGLNSISDVNKNGSIEGEDSKNNELQNSARCSNLVL 297

  Fly   115 -------QSQDDSEDVDLIFNEEGSCPLCNKTFS------------------RKSSLMTHIRNHS 154
                   :...|||       |.|:  .|.::|.                  ..|||....|...
Human   298 CQHIPKAERPTDSE-------EHGN--KCKQSFHMVTWHVLKPHKSDSGDSFHHSSLFETQRQLH 353

  Fly   155 AERKFVCTYCHKGFTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNE 219
            .||.:.|..|.|.|.|.::|..|:||||.::||.|.:|||:|:|...|..|:|.||||:|:.|  
Human   354 EERPYKCGNCGKSFKQRSDLFRHQRIHTGEKPYGCQECGKSFSQSAALTKHQRTHTGEKPYTC-- 416

  Fly   220 PECGRSFAQVTNLNNHMKSHHKVQQYCCNVCNKKFTQVTSLNQHLQAHAGVTGYYCPRCPEKNFK 284
            .:||..|.|.::||.|..:|.:.:.:.|..|.:. ..:::|.:|.:.|.|...|.|..| ||:||
Human   417 LKCGERFRQNSHLNRHQSTHSRDKHFKCEECGET-CHISNLFRHQRLHKGERPYKCEEC-EKSFK 479

  Fly   285 LQSQLHTHMKTHGLAFPYECDKCDEKFLQQAHLDQHLKMH-DEFKFKCDICPSSFNQESLLKKHV 348
            .:|.|..|.:.|....||.|..|.::|.|.|.|.:|.::| .|..:||..|...|.|.:.|.:| 
Human   480 QRSDLFKHHRIHTGEKPYGCSVCGKRFNQSATLIKHQRIHTGEKPYKCLECGERFRQSTHLIRH- 543

  Fly   349 QRHVEGRYLS 358
            ||..:.:.||
Human   544 QRIHQNKVLS 553

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32772NP_001284870.1 COG5048 <124..378 CDD:227381 85/254 (33%)
C2H2 Zn finger 133..153 CDD:275368 6/37 (16%)
zf-H2C2_2 145..170 CDD:290200 9/24 (38%)
C2H2 Zn finger 161..181 CDD:275368 8/19 (42%)
zf-H2C2_2 173..198 CDD:290200 13/24 (54%)
C2H2 Zn finger 189..209 CDD:275368 9/19 (47%)
C2H2 Zn finger 217..239 CDD:275368 8/21 (38%)
zf-H2C2_2 231..256 CDD:290200 6/24 (25%)
C2H2 Zn finger 247..267 CDD:275368 4/19 (21%)
C2H2 Zn finger 275..296 CDD:275368 9/20 (45%)
C2H2 Zn finger 304..324 CDD:275368 7/19 (37%)
C2H2 Zn finger 331..351 CDD:275368 7/19 (37%)
C2H2 Zn finger 359..380 CDD:275368 99/335 (30%)
ZNF394NP_115540.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..61
SCAN 60..170 CDD:128708
KRAB_A-box 155..214 CDD:322003
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 182..201
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 231..285 7/51 (14%)
C2H2 Zn finger 337..353 CDD:275368 4/15 (27%)
COG5048 356..>420 CDD:227381 29/65 (45%)
C2H2 Zn finger 360..380 CDD:275368 8/19 (42%)
C2H2 Zn finger 388..408 CDD:275368 9/19 (47%)
zf-C2H2 414..436 CDD:306579 8/23 (35%)
C2H2 Zn finger 416..436 CDD:275368 8/21 (38%)
C2H2 Zn finger 444..463 CDD:275368 4/19 (21%)
SFP1 <464..543 CDD:227516 29/79 (37%)
C2H2 Zn finger 471..491 CDD:275368 9/20 (45%)
C2H2 Zn finger 499..519 CDD:275368 7/19 (37%)
C2H2 Zn finger 527..547 CDD:275368 8/20 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23226
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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