DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG32772 and ZNF215

DIOPT Version :9

Sequence 1:NP_001284870.1 Gene:CG32772 / 31420 FlyBaseID:FBgn0052772 Length:520 Species:Drosophila melanogaster
Sequence 2:NP_001341782.1 Gene:ZNF215 / 7762 HGNCID:13007 Length:517 Species:Homo sapiens


Alignment Length:226 Identity:71/226 - (31%)
Similarity:114/226 - (50%) Gaps:21/226 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   111 SENLQSQDDSEDVDL------IFNEEGSCPLCN--KTFSRKSSLMTHIRNHSAERKFVCTYCHKG 167
            |||.:|.|.:....:      |.:.:|| |.|:  ||:. |.:|.:..:.|| |.::     ...
Human   304 SENKKSFDINSVSSICAIQVGIPSRKGS-PKCDKFKTYF-KFNLDSVGKQHS-EYEY-----GND 360

  Fly   168 FTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNL 232
            .:.:.::| |::.||....|:|..|||.|.:.::|..|:.:||||:|:.|:  ||||.|.:.|||
Human   361 LSLSTDIR-HQKSHTTMNSYECYQCGKAFCRSSSLIRHQIIHTGEKPYKCS--ECGRFFNRRTNL 422

  Fly   233 NNHMKSHHKVQQYCCNVCNKKFTQVTSLNQHLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHG 297
            ..|.|.|.:.:....|.|.|.|::....| :...|.|...|.|..| .|:|...|.|..|...|.
Human   423 TKHQKLHAEAKACTSNKCGKAFSKSEDSN-NPTLHFGNNFYQCVNC-GKSFNRSSSLIRHQMIHT 485

  Fly   298 LAFPYECDKCDEKFLQQAHLDQHLKMHDEFK 328
            ...|::|.:|.:.|.:.::|.:|.|:|...|
Human   486 GEKPFKCKECSKAFNRSSNLVKHQKLHTRDK 516

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32772NP_001284870.1 COG5048 <124..378 CDD:227381 66/213 (31%)
C2H2 Zn finger 133..153 CDD:275368 6/21 (29%)
zf-H2C2_2 145..170 CDD:290200 4/24 (17%)
C2H2 Zn finger 161..181 CDD:275368 2/19 (11%)
zf-H2C2_2 173..198 CDD:290200 10/24 (42%)
C2H2 Zn finger 189..209 CDD:275368 7/19 (37%)
C2H2 Zn finger 217..239 CDD:275368 11/21 (52%)
zf-H2C2_2 231..256 CDD:290200 9/24 (38%)
C2H2 Zn finger 247..267 CDD:275368 5/19 (26%)
C2H2 Zn finger 275..296 CDD:275368 7/20 (35%)
C2H2 Zn finger 304..324 CDD:275368 6/19 (32%)
C2H2 Zn finger 331..351 CDD:275368
C2H2 Zn finger 359..380 CDD:275368
ZNF215NP_001341782.1 SCAN 44..132 CDD:307924
KRAB 164..226 CDD:214630
zf-C2H2 379..401 CDD:306579 8/21 (38%)
C2H2 Zn finger 381..401 CDD:275368 7/19 (37%)
zf-H2C2_2 393..418 CDD:316026 13/26 (50%)
C2H2 Zn finger 409..484 CDD:275368 27/78 (35%)
C2H2 Zn finger 412..429 CDD:275368 9/16 (56%)
COG5048 436..>517 CDD:227381 25/83 (30%)
C2H2 Zn finger 492..512 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23226
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.