DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32772 and ZNF174

DIOPT Version :9

Sequence 1:	NP_001284870.1	Gene:	CG32772 / 31420	FlyBaseID:	FBgn0052772	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001334797.1	Gene:	ZNF174 / 7727	HGNCID:	12963	Length:	407	Species:	Homo sapiens

Alignment Length:	189	Identity:	58/189 - (30%)
Similarity:	96/189 - (50%)	Gaps:	17/189 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 AAAAATSSSTASSSDSDAIAQQQQHQNPQQQQHQNSQQQQQQQQQMQSSSSSENLQSQDDSEDVD 124
            |..|...:.:|..|..:.:      ||| :.:..|..:.:..::|:.|.::.:..........|:
Human   226 AKGAKPCAVSAGRSKGNGL------QNP-EPRGANMSEPRLSRRQVSSPNAQKPFAHYQRHCRVE 283

  Fly   125 LIFNEEGSCPL--CNKTFSRKSSL------MTHIRNHSAERKFVCTYCHKGFTQAANLRNHERIH 181
            .|.:...|.||  ..|:...|.||      :.|....||::.:.|..|.|.||..:.|:.|:|:|
Human   284 YISSPLKSHPLRELKKSKGGKRSLSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVH 348

  Fly   182 TNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHH 240
            |.:|||.|.:||..|.:.:.|..|:|:||||:|:.|.  :||:||.|.:||:.|.:.||
Human   349 TGERPYTCGECGNCFGRQSTLKLHQRIHTGEKPYQCG--QCGKSFRQSSNLHQHHRLHH 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32772	NP_001284870.1	COG5048	<124..378	CDD:227381	47/125 (38%)
		C2H2 Zn finger	133..153	CDD:275368	7/27 (26%)
		zf-H2C2_2	145..170	CDD:290200	9/30 (30%)
		C2H2 Zn finger	161..181	CDD:275368	8/19 (42%)
		zf-H2C2_2	173..198	CDD:290200	12/24 (50%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		C2H2 Zn finger	217..239	CDD:275368	9/21 (43%)
		zf-H2C2_2	231..256	CDD:290200	5/10 (50%)
		C2H2 Zn finger	247..267	CDD:275368
		C2H2 Zn finger	275..296	CDD:275368
		C2H2 Zn finger	304..324	CDD:275368
		C2H2 Zn finger	331..351	CDD:275368
		C2H2 Zn finger	359..380	CDD:275368
ZNF174	NP_001334797.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
ZNF174	NP_001334797.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	150..270		10/50 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100