DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32772 and ZKSCAN1

DIOPT Version :9

Sequence 1:NP_001284870.1 Gene:CG32772 / 31420 FlyBaseID:FBgn0052772 Length:520 Species:Drosophila melanogaster
Sequence 2:NP_001333510.1 Gene:ZKSCAN1 / 7586 HGNCID:13101 Length:563 Species:Homo sapiens


Alignment Length:275 Identity:85/275 - (30%)
Similarity:139/275 - (50%) Gaps:21/275 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 SAAAAATSSSTASSSDSDAIAQQQQHQNPQQQQHQNSQQQQQQQQQMQSSSSSENLQSQDD---- 119
            |.:.|.||..:||..::...:|::..:...|:.....:||:..:::.:.       :.:|.    
Human   277 STSKAETSEDSASRGETTGRSQKEFGEKRDQEGKTGERQQKNPEEKTRK-------EKRDSGPAI 334

  Fly   120 SEDVDLIFNEEGSCPL-----CNKTFSRKSSLMTHIRNHSAERKFVCTYCHKGFTQAANLRNHER 179
            .:|...|..|.|  |.     ..::||..|:..|.....:..:...|..|.|.||::::|..|:.
Human   335 GKDKKTITGERG--PREKGKGLGRSFSLSSNFTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKI 397

  Fly   180 IHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQ 244
            |||.::||:|.:|||.|:..:||..|:|:||||:|..||  |||::|:..:||..|.:.|...:.
Human   398 IHTGEKPYECSECGKAFSLNSNLVLHQRIHTGEKPHECN--ECGKAFSHSSNLILHQRIHSGEKP 460

  Fly   245 YCCNVCNKKFTQVTSLNQHLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHGLAFPYECDKCDE 309
            |.||.|.|.|:|.:.|.:|.:.|.|...|.|..| .|.|...|.|..|.:.|....||:|.||.:
Human   461 YECNECGKAFSQSSDLTKHQRIHTGEKPYECSEC-GKAFNRNSYLILHRRIHTREKPYKCTKCGK 524

  Fly   310 KFLQQAHLDQHLKMH 324
            .|.:.:.|..|.::|
Human   525 AFTRSSTLTLHHRIH 539

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32772NP_001284870.1 COG5048 <124..378 CDD:227381 73/206 (35%)
C2H2 Zn finger 133..153 CDD:275368 5/24 (21%)
zf-H2C2_2 145..170 CDD:290200 5/24 (21%)
C2H2 Zn finger 161..181 CDD:275368 7/19 (37%)
zf-H2C2_2 173..198 CDD:290200 12/24 (50%)
C2H2 Zn finger 189..209 CDD:275368 9/19 (47%)
C2H2 Zn finger 217..239 CDD:275368 9/21 (43%)
zf-H2C2_2 231..256 CDD:290200 10/24 (42%)
C2H2 Zn finger 247..267 CDD:275368 8/19 (42%)
C2H2 Zn finger 275..296 CDD:275368 7/20 (35%)
C2H2 Zn finger 304..324 CDD:275368 6/19 (32%)
C2H2 Zn finger 331..351 CDD:275368
C2H2 Zn finger 359..380 CDD:275368
ZKSCAN1NP_001333510.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..51
SCAN 52..162 CDD:128708
KRAB_A-box 227..262 CDD:143639
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 257..373 20/104 (19%)
C2H2 Zn finger 355..371 CDD:275368 4/15 (27%)
COG5048 <356..537 CDD:227381 68/183 (37%)
C2H2 Zn finger 379..399 CDD:275368 7/19 (37%)
C2H2 Zn finger 407..427 CDD:275368 9/19 (47%)
C2H2 Zn finger 435..455 CDD:275368 9/21 (43%)
C2H2 Zn finger 463..483 CDD:275368 8/19 (42%)
C2H2 Zn finger 491..511 CDD:275368 7/20 (35%)
C2H2 Zn finger 519..539 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23226
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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