DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32772 and ZNF32

DIOPT Version :9

Sequence 1:	NP_001284870.1	Gene:	CG32772 / 31420	FlyBaseID:	FBgn0052772	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001311093.1	Gene:	ZNF32 / 7580	HGNCID:	13095	Length:	277	Species:	Homo sapiens

Alignment Length:	228	Identity:	88/228 - (38%)
Similarity:	126/228 - (55%)	Gaps:	11/228 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 QNSQQQQQQQQQMQSSSSSENLQSQDDSEDVDLIFNEEGSCPLCNKTFSRKSSLMTHIRNHSAER 157
            |||.::::.:|:   |..|:.|  |:||..|.....|   |..|.|:|.:|.||..|.|.|:.::
Human    51 QNSFRREKLEQK---SPDSKTL--QEDSPGVRQRVYE---CQECGKSFRQKGSLTLHERIHTGQK 107

  Fly   158 KFVCTYCHKGFTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPEC 222
            .|.||:|.|.|....||..|:||||.::||||.:|||:|:|..:|..|.|||||::|:.|  ..|
Human   108 PFECTHCGKSFRAKGNLVTHQRIHTGEKPYQCKECGKSFSQRGSLAVHERLHTGQKPYEC--AIC 170

  Fly   223 GRSFAQVTNLNNHMKSHHKVQQYCCNVCNKKFTQVTSLNQHLQAHAGVTGYYCPRCPEKNFKLQS 287
            .|||...:||..|.:.|...:.|.|:.|.|.|:|..||..|::.|.|:..|.|.:| .|:|..:.
Human   171 QRSFRNQSNLAVHRRVHSGEKPYRCDQCGKAFSQKGSLIVHIRVHTGLKPYACTQC-RKSFHTRG 234

  Fly   288 QLHTHMKTHGLAFPYECDKCDEKFLQQAHLDQH 320
            ....|.|.|....||.|.:|.:.|.|:..|..|
Human   235 NCILHGKIHTGETPYLCGQCGKSFTQRGSLAVH 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32772	NP_001284870.1	COG5048	<124..378	CDD:227381	77/197 (39%)
		C2H2 Zn finger	133..153	CDD:275368	9/19 (47%)
		zf-H2C2_2	145..170	CDD:290200	11/24 (46%)
		C2H2 Zn finger	161..181	CDD:275368	9/19 (47%)
		zf-H2C2_2	173..198	CDD:290200	15/24 (63%)
		C2H2 Zn finger	189..209	CDD:275368	9/19 (47%)
		C2H2 Zn finger	217..239	CDD:275368	8/21 (38%)
		zf-H2C2_2	231..256	CDD:290200	9/24 (38%)
		C2H2 Zn finger	247..267	CDD:275368	8/19 (42%)
		C2H2 Zn finger	275..296	CDD:275368	6/20 (30%)
		C2H2 Zn finger	304..324	CDD:275368	6/17 (35%)
		C2H2 Zn finger	331..351	CDD:275368
		C2H2 Zn finger	359..380	CDD:275368
ZNF32	NP_001311093.1	COG5048	<51..241	CDD:227381	78/200 (39%)
		C2H2 Zn finger	83..103	CDD:275368	9/19 (47%)
		C2H2 Zn finger	111..131	CDD:275368	9/19 (47%)
		C2H2 Zn finger	139..159	CDD:275368	9/19 (47%)
		C2H2 Zn finger	167..187	CDD:275368	8/21 (38%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	6/20 (30%)
		C2H2 Zn finger	251..269	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100