DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32772 and OVOL2

DIOPT Version :9

Sequence 1:	NP_001284870.1	Gene:	CG32772 / 31420	FlyBaseID:	FBgn0052772	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_067043.2	Gene:	OVOL2 / 58495	HGNCID:	15804	Length:	275	Species:	Homo sapiens

Alignment Length:	236	Identity:	58/236 - (24%)
Similarity:	108/236 - (45%)	Gaps:	40/236 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 AASASAAVAASAAAAATSSSTASSSDSDAIAQQQQHQNPQQQQHQNSQQQQQQQQQMQSSSSSEN 113
            ::|.|.:.:|.....|.|||:..:.:|:. .:....:.|  ..|..::|:...:.:::.::.:.:
Human    53 SSSGSGSSSAGEPGGAESSSSPHAPESET-PEPGDAEGP--DGHLATKQRPVARSKIKFTTGTCS 114

  Fly   114 LQSQDDSEDVDLIFNEEGSCPLCNKTFSRKSSLMTHIRNHSAERKFVCTYCHKGFTQAANLRNHE 178
                      |.:.:   ||.||.|.|..:..|..|::.|:..::.:||:|.|||....:|:.|.
Human   115 ----------DSVVH---SCDLCGKGFRLQRMLNRHLKCHNQVKRHLCTFCGKGFNDTFDLKRHV 166

  Fly   179 RIHTNDRPYQCVDCGKTFTQITNLNNH-RRLH----------TGERPFVCNEPECGRSFAQVTNL 232
            |.||..|||:|..|.|.|||..:|.:| :::|          ..::.:||.  :||.:.....:|
Human   167 RTHTGIRPYKCNVCNKAFTQRCSLESHLKKIHGVQQQYAYKQRRDKLYVCE--DCGYTGPTQEDL 229

  Fly   233 NNHMKSHH-------KVQQYCCNVCNKKFTQV----TSLNQ 262
            ..|:.|.|       |..:....:...|.|..    |||::
Human   230 YLHVNSAHPGSSFLKKTSKKLAALLQGKLTSAHQENTSLSE 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32772	NP_001284870.1	COG5048	<124..378	CDD:227381	47/161 (29%)
		C2H2 Zn finger	133..153	CDD:275368	7/19 (37%)
		zf-H2C2_2	145..170	CDD:290200	9/24 (38%)
		C2H2 Zn finger	161..181	CDD:275368	9/19 (47%)
		zf-H2C2_2	173..198	CDD:290200	12/24 (50%)
		C2H2 Zn finger	189..209	CDD:275368	8/20 (40%)
		C2H2 Zn finger	217..239	CDD:275368	5/21 (24%)
		zf-H2C2_2	231..256	CDD:290200	6/31 (19%)
		C2H2 Zn finger	247..267	CDD:275368	5/20 (25%)
		C2H2 Zn finger	275..296	CDD:275368
		C2H2 Zn finger	304..324	CDD:275368
		C2H2 Zn finger	331..351	CDD:275368
		C2H2 Zn finger	359..380	CDD:275368
OVOL2	NP_067043.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	15..101		11/50 (22%)
		C2H2 Zn finger	121..141	CDD:275368	7/19 (37%)
		C2H2 Zn finger	149..169	CDD:275368	9/19 (47%)
		zf-H2C2_2	161..186	CDD:316026	12/24 (50%)
		C2H2 Zn finger	177..198	CDD:275368	8/20 (40%)
		C2H2 Zn finger	216..233	CDD:275368	4/18 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000