DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32772 and si:dkeyp-53d3.3

DIOPT Version :9

Sequence 1:	NP_001284870.1	Gene:	CG32772 / 31420	FlyBaseID:	FBgn0052772	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001082865.2	Gene:	si:dkeyp-53d3.3 / 562337	ZFINID:	ZDB-GENE-050208-644	Length:	244	Species:	Danio rerio

Alignment Length:	220	Identity:	77/220 - (35%)
Similarity:	112/220 - (50%)	Gaps:	4/220 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 CPLCNKTFSRKSSLMTHIRNHSAERKFVCTYCHKGFTQAANLRNHERIHTNDRPYQCVDCGKTFT 197
            |..|.|..|.|.:...|:|.|:.|..::||.|.|..:.:...:.|..||:.::||.|..||..|.
Zfish    21 CTECGKNLSCKRTFTCHMRIHTGEGPYICTQCGKCLSSSETFKFHMMIHSGEKPYTCTQCGMIFR 85

  Fly   198 QITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCNKKFTQVTSLNQ 262
            |..:|..|..|||||:...|:  :||::|.:...|..|.:.|...:.|.|:.|.|.|.:...|.:
Zfish    86 QSPSLRRHLLLHTGEKRHKCD--QCGKTFLRGAQLKIHRRVHTNEKPYSCSECGKGFIRPAHLRR 148

  Fly   263 HLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHGLAFPYECDKCDEKFLQQAHLDQHLKMH-DE 326
            |.:.|.||..|.|.:| ||.|.....|..|..||....||:|..||:.|.:..||..|:::| .|
Zfish   149 HEKTHTGVREYMCFQC-EKTFVTAGALKRHQMTHTGEKPYKCAHCDKLFTRTEHLKVHMRIHTGE 212

  Fly   327 FKFKCDICPSSFNQESLLKKHVQRH 351
            ....|..|.:||.|.:.||.|::.|
Zfish   213 KPCTCTRCGTSFAQLASLKYHMRSH 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32772	NP_001284870.1	COG5048	<124..378	CDD:227381	77/220 (35%)
		C2H2 Zn finger	133..153	CDD:275368	7/19 (37%)
		zf-H2C2_2	145..170	CDD:290200	8/24 (33%)
		C2H2 Zn finger	161..181	CDD:275368	5/19 (26%)
		zf-H2C2_2	173..198	CDD:290200	9/24 (38%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		C2H2 Zn finger	217..239	CDD:275368	6/21 (29%)
		zf-H2C2_2	231..256	CDD:290200	8/24 (33%)
		C2H2 Zn finger	247..267	CDD:275368	6/19 (32%)
		C2H2 Zn finger	275..296	CDD:275368	7/20 (35%)
		C2H2 Zn finger	304..324	CDD:275368	7/19 (37%)
		C2H2 Zn finger	331..351	CDD:275368	8/19 (42%)
		C2H2 Zn finger	359..380	CDD:275368
si:dkeyp-53d3.3	NP_001082865.2	COG5048	<2..177	CDD:227381	54/158 (34%)
		C2H2 Zn finger	21..41	CDD:275368	7/19 (37%)
		C2H2 Zn finger	49..69	CDD:275368	5/19 (26%)
		C2H2 Zn finger	77..97	CDD:275368	7/19 (37%)
		zf-H2C2_2	89..114	CDD:290200	11/26 (42%)
		COG5048	<101..238	CDD:227381	47/140 (34%)
		C2H2 Zn finger	105..125	CDD:275368	6/21 (29%)
		C2H2 Zn finger	133..153	CDD:275368	6/19 (32%)
		C2H2 Zn finger	161..181	CDD:275368	7/20 (35%)
		zf-H2C2_2	173..198	CDD:290200	10/24 (42%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		zf-H2C2_2	201..226	CDD:290200	9/24 (38%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100