DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32772 and gl

DIOPT Version :9

Sequence 1:	NP_001284870.1	Gene:	CG32772 / 31420	FlyBaseID:	FBgn0052772	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001262708.1	Gene:	gl / 42210	FlyBaseID:	FBgn0004618	Length:	679	Species:	Drosophila melanogaster

Alignment Length:	291	Identity:	91/291 - (31%)
Similarity:	140/291 - (48%)	Gaps:	49/291 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 VRCSE-QLTNNSNFHQSAAAAAAV-------------AASASAAVAASAAAAATSSSTA------ 70
            ::||: ..|..||...:|||||||             .|||:.:..|...|.|.:...|
  Fly   300 MQCSQMNWTPPSNSTSAAAAAAAVNVLYPPLLSPGHYPASATYSFTADFRAPAPTGLGALPPLTV 364

  Fly    71 --SSSDSDAIAQQQQHQNPQQQQHQNSQQQQQQQQQMQSSSSSENLQS----QDDSEDVDLIFNE 129
              ..|.|...........|....:|......:.....|:::...:|.:    :|.:||:|   .:
  Fly   365 GEKESPSPPANSSLAGYYPTGVGNQGYTPPHKSPTSYQAAALGLSLSAFEDEEDSNEDLD---GD 426

  Fly   130 EGS---------CPLCNKTFSRKSSLMTHIRNHSAERKFVCTYCHKGFTQAANLRNHERIHTNDR 185
            |||         |.||.||::|.|:|.||:|.||.||.:.|..|:|.|:|||||..|.|.||..:
  Fly   427 EGSSGGEMKPNLCRLCGKTYARPSTLKTHLRTHSGERPYRCPDCNKSFSQAANLTAHVRTHTGQK 491

  Fly   186 PYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVC 250
            |::|..|.:.|:|.:::..|.|.|:||||:.|:  .|.:||:..:.|..|::.|...:.|.|.:|
  Fly   492 PFRCPICDRRFSQSSSVTTHMRTHSGERPYRCS--SCKKSFSDSSTLTKHLRIHSGEKPYQCKLC 554

  Fly   251 NKKFTQVTSLNQHLQAHA---------GVTG 272
            ..:|:|..:||:|::.|.         |.||
  Fly   555 LLRFSQSGNLNRHMRVHGNNNSSNGSNGATG 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32772	NP_001284870.1	COG5048	<124..378	CDD:227381	63/167 (38%)
		C2H2 Zn finger	133..153	CDD:275368	11/19 (58%)
		zf-H2C2_2	145..170	CDD:290200	12/24 (50%)
		C2H2 Zn finger	161..181	CDD:275368	11/19 (58%)
		zf-H2C2_2	173..198	CDD:290200	10/24 (42%)
		C2H2 Zn finger	189..209	CDD:275368	6/19 (32%)
		C2H2 Zn finger	217..239	CDD:275368	6/21 (29%)
		zf-H2C2_2	231..256	CDD:290200	7/24 (29%)
		C2H2 Zn finger	247..267	CDD:275368	7/19 (37%)
		C2H2 Zn finger	275..296	CDD:275368
		C2H2 Zn finger	304..324	CDD:275368
		C2H2 Zn finger	331..351	CDD:275368
		C2H2 Zn finger	359..380	CDD:275368
gl	NP_001262708.1	C2H2 Zn finger	439..459	CDD:275368	11/19 (58%)
		zf-C2H2	439..459	CDD:278523	11/19 (58%)
		zf-H2C2_2	452..476	CDD:290200	12/23 (52%)
		C2H2 Zn finger	467..487	CDD:275368	11/19 (58%)
		zf-H2C2_2	479..504	CDD:290200	10/24 (42%)
		zf-C2H2_8	492..570	CDD:292531	27/79 (34%)
		C2H2 Zn finger	495..515	CDD:275368	6/19 (32%)
		zf-H2C2_2	507..531	CDD:290200	10/25 (40%)
		C2H2 Zn finger	523..543	CDD:275368	6/21 (29%)
		zf-H2C2_2	536..560	CDD:290200	7/23 (30%)
		C2H2 Zn finger	551..571	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23226
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010