DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG32772 and Zkscan2

DIOPT Version :9

Sequence 1:NP_001284870.1 Gene:CG32772 / 31420 FlyBaseID:FBgn0052772 Length:520 Species:Drosophila melanogaster
Sequence 2:XP_001079250.1 Gene:Zkscan2 / 368120 RGDID:1359568 Length:960 Species:Rattus norvegicus


Alignment Length:443 Identity:106/443 - (23%)
Similarity:172/443 - (38%) Gaps:114/443 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 CFQTATLFQVPGYSIPTC--VRCSEQLTNN-----------SNFHQSAAAAAAVAASASAAVAAS 59
            |.:.:.|:.|....:..|  :|..||....           .|.|  ...:.|......|.|...
  Rat   517 CHRKSKLYGVVAEQLRECGFLRTPEQCRTKFKSLQKSYRKVKNGH--VLESCAFYKEMDALVNCR 579

  Fly    60 AAAAATSSSTASSSDSDAIAQQQQHQNPQQQQHQNSQQQQQQQQQMQSSSSSENLQSQDDSED-- 122
            .||..|::|....|.|   .|::.|...:.|:....:.::..|:.:...|.||.:..::.:|:  
  Rat   580 TAALPTNTSEEIPSLS---RQERGHIEVEPQEPTTWEPEESSQEAVLEDSGSERMSEEEITEEPE 641

  Fly   123 ------------------------VDLIFNE-EGSCPLCNK------------------TFS--- 141
                                    ..:||.: |....|..|                  .||   
  Rat   642 FEGSAGLPQSPTDFEIGNIIKEAPTQVIFKDTESHRALIEKPKRFVSQNTNPSKYGKRECFSGRH 706

  Fly   142 -------RKSSLMTHIRN-------------------------------------HSAERKFVCT 162
                   |:..||:..|:                                     |..|..:.|.
  Rat   707 WENLQGVRQGKLMSQPRDTGKAVVHQRPFVGRRPYRLLKYGENFGRSARLVCRMTHQKENPYKCG 771

  Fly   163 YCHKGFTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFA 227
            .|.|.|.::.:|..|:||||.::|::|:||||:|...:|...|.|:||||:|:.|.  |||:.|:
  Rat   772 VCGKCFGRSRSLIRHQRIHTGEKPFKCLDCGKSFNDSSNFGAHLRIHTGEKPYRCR--ECGKCFS 834

  Fly   228 QVTNLNNHMKSHHKVQQYCCNVCNKKFTQVTSLNQHLQAHAGVTGYYCPRCPEKNFKLQSQLHTH 292
            |.::|..|.::|...:.|.|..|.|.||..:..:.|.:||.|...|.|..| ||:|...::...|
  Rat   835 QSSSLIIHQRTHTGEKPYQCEECGKSFTNSSHFSAHRRAHTGENPYKCGDC-EKSFNNCTRFREH 898

  Fly   293 MKTHGLAFPYECDKCDEKFLQQAHLDQHLKMHDEFKFKCDICPSSFNQESLLK 345
            .:.|....||.|.:|.:.|.:.:.|.:|.::|...| .....||.::.|:|||
  Rat   899 RRIHTGEKPYTCAQCGKHFNKSSFLTKHREIHIREK-PLPYSPSVYSPENLLK 950

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32772NP_001284870.1 COG5048 <124..378 CDD:227381 80/288 (28%)
C2H2 Zn finger 133..153 CDD:275368 8/84 (10%)
zf-H2C2_2 145..170 CDD:290200 9/61 (15%)
C2H2 Zn finger 161..181 CDD:275368 7/19 (37%)
zf-H2C2_2 173..198 CDD:290200 13/24 (54%)
C2H2 Zn finger 189..209 CDD:275368 9/19 (47%)
C2H2 Zn finger 217..239 CDD:275368 8/21 (38%)
zf-H2C2_2 231..256 CDD:290200 8/24 (33%)
C2H2 Zn finger 247..267 CDD:275368 6/19 (32%)
C2H2 Zn finger 275..296 CDD:275368 6/20 (30%)
C2H2 Zn finger 304..324 CDD:275368 5/19 (26%)
C2H2 Zn finger 331..351 CDD:275368 6/15 (40%)
C2H2 Zn finger 359..380 CDD:275368
Zkscan2XP_001079250.1 SCAN 42..148 CDD:128708
SCAN 42..129 CDD:280241
KRAB <241..282 CDD:214630
Myb_DNA-bind_4 334..415 CDD:290549
ABC_trans_N <466..505 CDD:291196
Myb_DNA-bind_4 490..571 CDD:290549 10/55 (18%)
COG5048 <766..915 CDD:227381 56/151 (37%)
zf-C2H2 768..790 CDD:278523 7/21 (33%)
C2H2 Zn finger 770..790 CDD:275368 7/19 (37%)
zf-H2C2_2 782..806 CDD:290200 12/23 (52%)
C2H2 Zn finger 798..818 CDD:275368 9/19 (47%)
zf-H2C2_2 814..835 CDD:290200 12/22 (55%)
C2H2 Zn finger 826..846 CDD:275368 8/21 (38%)
zf-H2C2_2 838..863 CDD:290200 8/24 (33%)
C2H2 Zn finger 854..874 CDD:275368 6/19 (32%)
zf-H2C2_2 866..891 CDD:290200 10/25 (40%)
C2H2 Zn finger 882..902 CDD:275368 6/20 (30%)
zf-H2C2_2 895..918 CDD:290200 6/22 (27%)
C2H2 Zn finger 910..930 CDD:275368 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23226
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.