DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32772 and Zfp637

DIOPT Version :9

Sequence 1:	NP_001284870.1	Gene:	CG32772 / 31420	FlyBaseID:	FBgn0052772	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001333576.1	Gene:	Zfp637 / 232337	MGIID:	2448537	Length:	286	Species:	Mus musculus

Alignment Length:	256	Identity:	90/256 - (35%)
Similarity:	131/256 - (51%)	Gaps:	29/256 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 SSSTASSSDSDAIAQQQQHQNPQQQQHQNSQQQQQQQQQMQSSSSSENLQSQDDSEDV-DLIFNE 129
            |.:|.|||                ...|:|.::::.:|:     |.|:...|:||..| ..:::
Mouse    49 SEATGSSS----------------WDFQSSFRREKLEQK-----SPESKALQEDSPGVRQKVYD- 91

  Fly   130 EGSCPLCNKTFSRKSSLMTHIRNHSAERKFVCTYCHKGFTQAANLRNHERIHTNDRPYQCVDCGK 194
               |..|.|:|.:|.||..|.|.|:.::.|.||.|.|.|....||..|:||||.::||||.:|||
Mouse    92 ---CQECGKSFRQKGSLTLHERIHTGQKPFECTQCGKSFRAKGNLVTHQRIHTGEKPYQCKECGK 153

  Fly   195 TFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCNKKFTQVTS 259
            :|:|..:|..|.|||||::|:.|  ..|.|||...:||..|.:.|...:.|.|:.|.|.|:|..|
Mouse   154 SFSQRGSLAVHERLHTGQKPYEC--AICQRSFRNQSNLAVHRRVHSGEKPYRCDQCGKAFSQKGS 216

  Fly   260 LNQHLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHGLAFPYECDKCDEKFLQQAHLDQH 320
            |..|::.|.|:..|.|..| .|:|..:.....|.|.|....||.|.:|.:.|.|:..|..|
Mouse   217 LIVHIRVHTGLKPYACSHC-RKSFHTRGNCLLHGKVHTGETPYLCGQCGKSFTQRGSLAVH 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32772	NP_001284870.1	COG5048	<124..378	CDD:227381	76/197 (39%)
		C2H2 Zn finger	133..153	CDD:275368	9/19 (47%)
		zf-H2C2_2	145..170	CDD:290200	11/24 (46%)
		C2H2 Zn finger	161..181	CDD:275368	9/19 (47%)
		zf-H2C2_2	173..198	CDD:290200	15/24 (63%)
		C2H2 Zn finger	189..209	CDD:275368	9/19 (47%)
		C2H2 Zn finger	217..239	CDD:275368	8/21 (38%)
		zf-H2C2_2	231..256	CDD:290200	9/24 (38%)
		C2H2 Zn finger	247..267	CDD:275368	8/19 (42%)
		C2H2 Zn finger	275..296	CDD:275368	6/20 (30%)
		C2H2 Zn finger	304..324	CDD:275368	6/17 (35%)
		C2H2 Zn finger	331..351	CDD:275368
		C2H2 Zn finger	359..380	CDD:275368
Zfp637	NP_001333576.1	COG5048	<60..251	CDD:227381	75/202 (37%)
		C2H2 Zn finger	92..112	CDD:275368	9/19 (47%)
		C2H2 Zn finger	120..140	CDD:275368	9/19 (47%)
		C2H2 Zn finger	148..168	CDD:275368	9/19 (47%)
		C2H2 Zn finger	176..196	CDD:275368	8/21 (38%)
		C2H2 Zn finger	204..224	CDD:275368	8/19 (42%)
		C2H2 Zn finger	232..252	CDD:275368	6/20 (30%)
		C2H2 Zn finger	260..278	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100