DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32772 and znf1155

DIOPT Version :9

Sequence 1:	NP_001284870.1	Gene:	CG32772 / 31420	FlyBaseID:	FBgn0052772	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_009294134.1	Gene:	znf1155 / 101885074	ZFINID:	ZDB-GENE-050208-712	Length:	456	Species:	Danio rerio

Alignment Length:	443	Identity:	119/443 - (26%)
Similarity:	198/443 - (44%)	Gaps:	56/443 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 AAAATSSSTASSSDSDAIAQQQQHQNPQQQQHQNS--------QQQQQQQQQMQSSSSSENL--- 114
            :|...|.|..||..|.|...::|.|:..:...:.|        |::.::...::....||.|
Zfish     3 SALTRSPSVESSELSSAAISERQMQSLLKDSEKMSDPEPCRIKQEETEELIDVKVKEESEELSEA 67

  Fly   115 ----------QSQDDSEDVDLIFNEEG--SCPLCNKTFSRKSSLMTHIRNHSAERKFVCTYCHKG 167
                      ::|.::||..:|.....  :|..|.|:|..|..|..|:..|:.|:.:.|::|.|.
Zfish    68 EEKHHVKREEETQSETEDSFVIERTVSGFTCAQCGKSFRHKYHLKRHMIIHTGEKPYQCSHCDKR 132

  Fly   168 FTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNL 232
            |..:.||.:|..:||.::.::|..|||||.:.:.|.:||.:||.::|:.|:  |||.||:..:||
Zfish   133 FGDSGNLNSHMLVHTGEKTHKCDQCGKTFMRFSELKSHRTVHTNKKPYSCS--ECGNSFSNWSNL 195

  Fly   233 NNHMKSHHKVQQYCCNVCNKKFTQVTSLNQHLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHG 297
            ..|.|.|..|:::.|..|.|.|.:...|..|.:.|.|...|.|..| :|:|.....|..|.:||.
Zfish   196 KAHQKIHTGVREFVCFDCGKSFIRAGGLKNHQRIHTGEKPYKCSHC-DKSFNQLQILKVHRRTHT 259

  Fly   298 LAFPYECDKCDEKFLQQAHLDQHLKMH-DEFKFKCDICPSSFNQESLLKKHVQRHVEGRYLSCPV 361
            ...||.|..|.:.|.|..:..:||.:| .|...|||.|..:|...|.||.|::.|...:..:|
Zfish   260 GEKPYTCTHCGKSFRQSPNFYRHLLIHTGEKPHKCDHCSKTFLWPSELKDHLRVHTNEKPYAC-- 322

  Fly   362 ANCAESFAVRQHLSKHLLTNHAHHELPPPKRSK---KAGTLQTSQQPLAMIGQPLSLQHTTGQRG 423
            :.|.:||..:.:|.:|...:.:..:....:..|   ||.:|:               ||.|...|
Zfish   323 SECGKSFTQQSNLRQHQKIHASVRKFVCSECGKAFIKAVSLR---------------QHQTIHTG 372

  Fly   424 RPPKNKNKATTLAATAIKIEINESLHS-------QHISNVSGLSIQQQINQHM 469
            ..|....:.......|..::.:|.:|:       .|...  ..::...:|.||
Zfish   373 ERPYVCLQCNKTFRDAGYLKAHERIHTGEKPYTCTHCGR--SFTVSSSLNSHM 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32772	NP_001284870.1	COG5048	<124..378	CDD:227381	85/256 (33%)
		C2H2 Zn finger	133..153	CDD:275368	7/19 (37%)
		zf-H2C2_2	145..170	CDD:290200	8/24 (33%)
		C2H2 Zn finger	161..181	CDD:275368	7/19 (37%)
		zf-H2C2_2	173..198	CDD:290200	11/24 (46%)
		C2H2 Zn finger	189..209	CDD:275368	9/19 (47%)
		C2H2 Zn finger	217..239	CDD:275368	10/21 (48%)
		zf-H2C2_2	231..256	CDD:290200	10/24 (42%)
		C2H2 Zn finger	247..267	CDD:275368	6/19 (32%)
		C2H2 Zn finger	275..296	CDD:275368	6/20 (30%)
		C2H2 Zn finger	304..324	CDD:275368	6/19 (32%)
		C2H2 Zn finger	331..351	CDD:275368	8/19 (42%)
		C2H2 Zn finger	359..380	CDD:275368	6/20 (30%)
znf1155	XP_009294134.1	COG5048	79..454	CDD:227381	105/367 (29%)
		C2H2 Zn finger	98..118	CDD:275368	7/19 (37%)
		zf-H2C2_2	110..133	CDD:290200	7/22 (32%)
		C2H2 Zn finger	126..146	CDD:275368	7/19 (37%)
		zf-H2C2_2	138..161	CDD:290200	9/22 (41%)
		C2H2 Zn finger	154..174	CDD:275368	9/19 (47%)
		C2H2 Zn finger	182..202	CDD:275368	10/21 (48%)
		C2H2 Zn finger	210..230	CDD:275368	6/19 (32%)
		zf-H2C2_2	223..247	CDD:290200	9/24 (38%)
		C2H2 Zn finger	238..258	CDD:275368	6/20 (30%)
		zf-H2C2_2	251..275	CDD:290200	9/23 (39%)
		C2H2 Zn finger	266..286	CDD:275368	6/19 (32%)
		zf-H2C2_2	278..301	CDD:290200	8/22 (36%)
		C2H2 Zn finger	294..314	CDD:275368	8/19 (42%)
		zf-H2C2_2	306..331	CDD:290200	8/26 (31%)
		C2H2 Zn finger	322..342	CDD:275368	6/21 (29%)
		C2H2 Zn finger	350..370	CDD:275368	7/34 (21%)
		C2H2 Zn finger	378..398	CDD:275368	2/19 (11%)
		zf-H2C2_2	390..414	CDD:290200	3/25 (12%)
		C2H2 Zn finger	406..426	CDD:275368	4/20 (20%)
		zf-H2C2_2	418..443	CDD:290200	3/6 (50%)
		C2H2 Zn finger	434..454	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010