DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32772 and ZSCAN30

DIOPT Version :9

Sequence 1:	NP_001284870.1	Gene:	CG32772 / 31420	FlyBaseID:	FBgn0052772	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001106205.1	Gene:	ZSCAN30 / 100101467	HGNCID:	33517	Length:	494	Species:	Homo sapiens

Alignment Length:	332	Identity:	94/332 - (28%)
Similarity:	152/332 - (45%)	Gaps:	44/332 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 RCSEQLTNNSNFHQ---SAAAAAAVAASASAAVAASAAAAATSSSTASSSDSDAIAQQ------- 81
            :|..:...:..|.:   ...|...:.|........::||..:.......:.|..||::
Human   170 QCKTETQESQAFQERDGRMVAGKVLMAKQEIVECVASAAMISPGKLPGETHSQRIAEEALGGLDN 234

  Fly    82 --QQHQN---------PQQQQH------------QNSQQQQQQQQQMQSSSSSE-NLQSQDDSED 122
              :|..|         |.|.:|            ::|..:..:.:...|.:|:: ..||.|..|.
Human   235 SKKQKGNAAGNKISQLPSQDRHFSLATFNRRIPTEHSVLESHESEGSFSMNSNDITQQSVDTREK 299

  Fly   123 VDLIFNEEGSCPLCNKTFSRKSSLMTHIRNHSAERKFVCTYCHKGFTQAANLRNHERIHTNDRPY 187
            :...|:       |.|.|.:.|.|:.|.|.|:.||.:.|..|.|.|:.:::|..|:|||:.::||
Human   300 LYECFD-------CGKAFCQSSKLIRHQRIHTGERPYACKECGKAFSLSSDLVRHQRIHSGEKPY 357

  Fly   188 QCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCNK 252
            :|.:|||.|...:.|..|||:||||:|:.|.  |||::|::.:.|..|.|.|...:.|.|..|.|
Human   358 ECCECGKAFRGSSELIRHRRIHTGEKPYECG--ECGKAFSRSSALIQHKKIHTGDKSYECIACGK 420

  Fly   253 KFTQVTSLNQHLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHGLAFPYECDKCDEKFLQQAHL 317
            .|.:.:.|.:|.:.|.|...|.|..| .|:|...|.|..|.:.|....||||.:|.:.|..::.|
Human   421 AFGRSSILIEHQRIHTGEKPYECNEC-GKSFNQSSALTQHQRIHTGEKPYECSECRKTFRHRSGL 484

  Fly   318 DQHLKMH 324
            .||.:.|
Human   485 MQHQRTH 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32772	NP_001284870.1	COG5048	<124..378	CDD:227381	73/201 (36%)
		C2H2 Zn finger	133..153	CDD:275368	7/19 (37%)
		zf-H2C2_2	145..170	CDD:290200	10/24 (42%)
		C2H2 Zn finger	161..181	CDD:275368	7/19 (37%)
		zf-H2C2_2	173..198	CDD:290200	12/24 (50%)
		C2H2 Zn finger	189..209	CDD:275368	9/19 (47%)
		C2H2 Zn finger	217..239	CDD:275368	8/21 (38%)
		zf-H2C2_2	231..256	CDD:290200	9/24 (38%)
		C2H2 Zn finger	247..267	CDD:275368	6/19 (32%)
		C2H2 Zn finger	275..296	CDD:275368	7/20 (35%)
		C2H2 Zn finger	304..324	CDD:275368	6/19 (32%)
		C2H2 Zn finger	331..351	CDD:275368
		C2H2 Zn finger	359..380	CDD:275368
ZSCAN30	NP_001106205.1	SCAN	44..154	CDD:128708
		SCAN	44..122	CDD:280241
		COG5048	281..>360	CDD:227381	28/85 (33%)
		zf-C2H2	301..323	CDD:278523	8/28 (29%)
		C2H2 Zn finger	303..323	CDD:275368	8/26 (31%)
		zf-H2C2_2	316..339	CDD:290200	9/22 (41%)
		COG5048	<328..479	CDD:227381	57/153 (37%)
		C2H2 Zn finger	331..351	CDD:275368	7/19 (37%)
		zf-H2C2_2	343..366	CDD:290200	11/22 (50%)
		C2H2 Zn finger	359..379	CDD:275368	9/19 (47%)
		zf-H2C2_2	371..396	CDD:290200	14/26 (54%)
		C2H2 Zn finger	387..407	CDD:275368	8/21 (38%)
		zf-H2C2_2	399..424	CDD:290200	9/24 (38%)
		C2H2 Zn finger	415..435	CDD:275368	6/19 (32%)
		zf-H2C2_2	428..452	CDD:290200	9/24 (38%)
		C2H2 Zn finger	443..463	CDD:275368	7/20 (35%)
		zf-H2C2_2	455..480	CDD:290200	9/24 (38%)
		C2H2 Zn finger	471..491	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100