Protein Alignment CG6927 and glrb

DIOPT Version :9

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001072255.1
• Gene: glrb / 779708
• XenbaseID: XB-GENE-1011734
• Length: 497
• Species: Xenopus tropicalis
• Alignment Length: 528
• Identity: 141/528 - (26%)
• Similarity: 234/528 - (44%)
• Gaps: 100/528 - (18%)

  Fly    25 CPTLDDGDSL------SQTQLLDRLTHGCRYDRLERPITYSETGQRLPVDVYMRAYIYFMQNLEA 83
            ||:....:.|      |.:.:|:||.  ..||...||     ..:.:||||.:..:|....:::.
 Frog    39 CPSQLSAEDLARVPANSTSNILNRLL--VSYDPRVRP-----NFKGIPVDVVVNIFINSFGSIQE 96

  Fly    84 HDLQFKIYALLQMRYLDPRL----NFRNVSPKRRQPILGEEHLRNSLWMPHIFLANERDSSILGL 144
            ..:.:::...|:.|:.||||    :||........|.:.:     .||.|.:|.|||::::...:
 Frog    97 TTMDYRVNIFLRQRWNDPRLKLPNDFRGSDALTVDPTMFK-----CLWKPDLFFANEKNANFHDV 156

  Fly   145 TEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQHCSTVLESWMYNTSELVLHWEQKRPI 209
            |:::||..|..||.|::|.|:..||.|.|:|..||.|.|.|...|||:.|.|.:|...|:...|:
 Frog   157 TQENILLFIFRDGDVLLSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPV 221

  Fly   210 TYDGALHLTEFVLQRSWSNETVINADLSDLRHG------AFAGNYSSLSFTVHLTRVVGFYLMDY 268
            ..: .:.|.:|.::            ..|:.:|      ...|.|:.:.....|.|.||||:|..
 Frog   222 QME-KIALPQFDIK------------TEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGV 273

  Fly   269 FLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFITLASAQGKTLPKVSYIKVSEVWFLGCTI 333
            :.|::|||.:||:|||:..|.:..|:.||..::|:..:..:...:.||||||:|..:||.:.|.:
 Frog   274 YAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAQELPKVSYVKAIDVWLIACLL 338

  Fly   334 FIFGSMVEFAFVNTIWRRKKSVPVKKLNSKHILKSTLSPNLLRRRSHARSRSFSGTALHKTADTG 398
            |.|.|:||:|.|..:....|.:..:|..   |.|:..:.......:...:.:.:||.:|
 Frog   339 FGFASLVEYAVVQVLLNSPKRIEAEKAK---IAKAEQAEGKGANAAKKNTVNGTGTPIH------ 394

  Fly   399 SLGGAGFNNYLTVNLPITTIKEGQVLDQQRTSRV-VQKMDVNFVESAFGSMGSAQSTGAIS---- 458
                            |:|::.|    :.|..:| ..|.|:.  .:.|..:||......:|
 Frog   395 ----------------ISTLQVG----ENRCKKVCTSKSDLR--SNDFSIVGSLPRDFELSNYDC 437

  Fly   459 ---------AASSSQTLTNNNRTESAGHQEEIDLSGWTTLTPQEIAMWIDSRARFVFPLSFLVFN 514
                     ....||. .||.:...|           ..:.|.| |..||..:|.:||..||.||
 Frog   438 YGKPIEVNNGLGKSQA-KNNKKPPPA-----------KPVIPSE-AKRIDLYSRALFPFCFLFFN 489

  Fly   515 LFFWTFVY 522
            :.:| .||
 Frog   490 VIYW-LVY 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:273305	139/524 (27%)
		Neur_chan_LBD	36..259	CDD:280998	62/232 (27%)
		Neur_chan_memb	270..518	CDD:280999	66/261 (25%)
glrb	NP_001072255.1	LIC	38..496	CDD:273305	139/526 (26%)
		LGIC_ECD_GlyR_beta	79..265	CDD:349811	55/203 (27%)
		Cys-loop	183..197	CDD:349811	7/13 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010