Protein Alignment CG6927 and gabrg2

DIOPT Version :10

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_031754595.1
• Gene: gabrg2 / 779514
• XenbaseID: XB-GENE-5949005
• Length: 505
• Species: Xenopus tropicalis
• Alignment Length: 554
• Identity: 125/554 - (22%)
• Similarity: 209/554 - (37%)
• Gaps: 144/554 - (25%)

  Fly     5 LIISILLNCLYASASALDEDCPT---------LDDGDSLSQTQLLDRLTHGCRYDRLERPITYSE 60
            |:|...:.|.:.......||.|:         ..|.|   .|.:|:.|..|  ||...||    :
 Frog    59 LLILSFIQCSFQKDDEDYEDAPSNNTWLLTRKFHDND---VTSILNGLLKG--YDNKLRP----D 114

  Fly    61 TGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRRQPILGEEHLRNS 125
            .|.: |..::...|:..:..:.|.::::.|.......:.|.||.|.:.....|.    ..::...
 Frog   115 IGVK-PTVIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRL----NSNMVGK 174

  Fly   126 LWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQHCSTVLE 190
            :|:|..|..|.:.:....:|..:.:..|..||.|:.:.|:.....|.|.|..||.||..|.....
 Frog   175 IWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFS 239

  Fly   191 SWMYNTSELVLHWEQKRPITYD---GALHLTEFVLQRSWSNETVINADLSDLRHGAFAGNYSSLS 252
            |:.|...|::..|::......|   ..|:...||..|:.:.|....           :|:|..::
 Frog   240 SYGYPKEEIIYQWKRSSVEVGDVRSWRLYQFSFVGLRNTTEEVKTT-----------SGDYVVMT 293

  Fly   253 FTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFITLASAQGKTLPK 317
            ....|:|.:|::.:..::|..|||.:||||||:..|..|.|.:||.:|:||..||::...|:|||
 Frog   294 VYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPK 358

  Fly   318 VSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIWRRKKSVPVKKLNSKHILKSTLSPNLLRRRSHAR 382
            |||:...:::...|.||:|.:::|:
 Frog   359 VSYVTAMDLFVSVCFIFVFAALMEY---------------------------------------- 383

  Fly   383 SRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQVLDQQRTSRVVQKMDVNFVESAFGS 447
                 || ||               |...|              ::.|:..:|...|.:...|
 Frog   384 -----GT-LH---------------YFVSN--------------RKPSKDKEKKKKNPLLWMF-- 411

  Fly   448 MGSAQSTGAISAASSSQTLTNNNRTESAGHQEEIDLSGWTTLTPQEIA------------MW--- 497
               :.....|.....|.|:..||.|......||.   |:..|..::.|            .|
 Frog   412 ---SFKAPTIDIRPRSATIQMNNATHLQERDEEY---GYECLDGKDCASFFCCFEDCRTGAWRHG 470

  Fly   498 --------IDSRARFVFPLSFLVFNLFFW-TFVY 522
                    |||.:|..||.:|.:|||.:| :::|
 Frog   471 RIHIRVAKIDSYSRIFFPTAFCLFNLVYWVSYLY 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:455710	124/550 (23%)
gabrg2	XP_031754595.1	LIC	99..502	CDD:455710	115/507 (23%)
		LGIC_ECD_GABAAR_G	120..301	CDD:349801	39/195 (20%)
		Cys-loop	220..234	CDD:349801	7/13 (54%)