Protein Alignment CG6927 and gabrz

DIOPT Version :10

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001108214.2
• Gene: gabrz / 561738
• ZFINID: ZDB-GENE-080303-26
• Length: 447
• Species: Danio rerio
• Alignment Length: 549
• Identity: 134/549 - (24%)
• Similarity: 230/549 - (41%)
• Gaps: 147/549 - (26%)

  Fly     7 ISILLNCLYASASALDEDCPTLDDGDSLSQTQLL----DRLTHGCRYDRLERPITYSETGQRLPV 67
            :..||..|:.|         .:.||...:..::|    .:|..|  |::..||  :...|   ||
Zfish     7 VGFLLLLLFIS---------RIMDGSVANTEEILPPTIQKLMKG--YNKYLRP--FFGNG---PV 55

  Fly    68 DVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNF---RNVSPKRRQPILGEEHLRNSLWMP 129
            .|.|...|..:..:...::.:.....|:.|:.|.||.|   :::|...|        |...||:|
Zfish    56 TVGMSLDIASIDTISEINMDYTATIFLRQRWTDERLCFDGNKSLSLDGR--------LVELLWVP 112

  Fly   130 HIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQHCSTVLESWMY 194
            ..|:.:.:.|.:..:|.::.|..|.|:|||:.:.||..|:.|.::|.|:|.|.|.|...||||.|
Zfish   113 DTFIVDSKKSFLHDITVENRLIRIFPNGTVLYALRITTTVACSMDLTKYPMDRQTCMLQLESWGY 177

  Fly   195 NTSELVLHWEQ-KRPITYDGALHLTEFVLQRSWSNETVINADLSDLRHGAFAGNYSSLSFTVHLT 258
            |..::|.:|.: .:.::....|.|.::.|:..:::|:....:         .|||..|.|...|.
Zfish   178 NVKDVVFYWTRGNQSVSGLDHLQLAQYTLEDHYTSESEAVYE---------TGNYPKLIFHFKLK 233

  Fly   259 RVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFITLASAQGKTLPKVS-YIK 322
            |.:.:::::.::||..:|.:||||||:.....|.||.:|.:|:||..||......:||..: :||
Zfish   234 RSILYFILETYVPSSALVVLSWVSFWISQSSVPARICIGVTTVLTMTTLMMGARTSLPNANCFIK 298

  Fly   323 VSEVWFLGCTIFIFGSMVEFAFVNTIWRRKKSVPVKKLNSKHILKSTLSPNLLRRRSHARSRSFS 387
            ..:|:...|..||||:::|:|             |....:.|      .||
Zfish   299 AIDVYLGICFSFIFGALIEYA-------------VAHFCTLH------QPN-------------- 330

  Fly   388 GTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQVLDQQRTSRVVQKMDVNFVESAFGSMGSAQ 452
                            ..|.|:          .||.:.::..       ::|.:.::|||
Zfish   331 ----------------AANAYM----------YGQEMQERED-------EMNGIVTSFGS----- 357

  Fly   453 STGAISAASSSQTLTN----NNRTESAGHQEEIDLSGWTTLTPQ--------------------- 492
              .|:.|....:.|:.    ||.|.|.. :|::..|     .||
Zfish   358 --HALRARKREEMLSRMGSVNNPTPSES-KEDVSSS-----QPQTRCTKCMSRARRIIRCLYCCK 414

  Fly   493 -EIAMWIDSRARFVFPLSFLVFNLFFWTF 520
             |...:||:.:|..|||||::.||.:||:
Zfish   415 VENPHYIDNYSRLTFPLSFVIINLLYWTY 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:455710	133/547 (24%)
gabrz	NP_001108214.2	LIC	26..444	CDD:455710	128/521 (25%)
		LGIC_ECD_GABAAR_pi	54..235	CDD:349805	54/197 (27%)
		Cys-loop	153..168	CDD:349805	6/14 (43%)