Protein Alignment CG6927 and gabra6b

DIOPT Version :10

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_002667403.3
• Gene: gabra6b / 559693
• ZFINID: ZDB-GENE-080815-1
• Length: 444
• Species: Danio rerio
• Alignment Length: 543
• Identity: 142/543 - (26%)
• Similarity: 222/543 - (40%)
• Gaps: 131/543 - (24%)

  Fly     1 MEWSLIISILLNCLYAS-ASALDEDCPT-----LDDGDSLSQTQLLDRLTHGCRYDRLER----- 54
            |.|      :..||:.| ...:..:.||     ||     :.|::||||..|  ||...|
Zfish     1 MAW------VRTCLFLSCVGQVVANPPTETRIYLD-----NITRILDRLLDG--YDNRLRPGFGG 52

  Fly    55 PITYSETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRRQPILGE 119
            |:|..:|      |:::.::    ..:...::::.:....:..::|.||.|..       ||
Zfish    53 PVTEVKT------DIFVTSF----GPVSDVEMEYTMDVFFRQTWIDDRLKFEG-------PI--- 97

  Fly   120 EHLR------NSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKF 178
            |.||      :.:|.|..|..|.:.|....:|..:.|..|..:||::.:.|:.....|.:.|..|
Zfish    98 EILRLNNLMVSKIWTPDTFFRNGKRSISHNMTTPNKLFRIMQNGTILYTMRLTINAECPMRLINF 162

  Fly   179 PFDEQHCSTVLESWMYNTSELVLHWEQKRPITYDGALHLTEFVLQRSWS--NETVINADLSDLRH 241
            |.|...|.....|:.|..||:|..|::       |.|...| |.|.|.|  ...:|...:|..|.
Zfish   163 PMDGHSCPLKFGSYAYPMSEIVYTWKK-------GPLFSVE-VPQESSSLLQYDLIGQTVSSERL 219

  Fly   242 GAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFIT 306
            .:..|.|..::...||.|.:||:|:..::|.::.|.::.||||:..:..|.|...|.:|:||..|
Zfish   220 KSNTGEYIVMTVYFHLQRKMGFFLIQTYIPCIMTVILAQVSFWIDKESVPARTVFGITTVLTMTT 284

  Fly   307 LASAQGKTLPKVSYIKVSEVWFLG-CTIFIFGSMVEFAFVNTIWRRKKSVPVKKLNSKHILKSTL 370
            |:.:...:||||||....: ||:. |..|:|.:::|||.||..                   |||
Zfish   285 LSISARHSLPKVSYATAMD-WFIAVCFAFVFSALIEFAAVNYF-------------------STL 329

  Fly   371 SPNL-LRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQVLDQQRTSRVVQ 434
            ..|. |||.:.||:.:.:..|   .:|     |.|..|         .:..|.||.::
Zfish   330 QANKELRRANIARAAAAAAAA---RSD-----GEGVLN---------PLDPGGVLKKR------- 370

  Fly   435 KMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNRTESAGHQEEIDLSGWTTLTPQEIAMWID 499
                      ..|:....:|...|..|.|..           ||:...:.....|....|   ||
Zfish   371 ----------MNSLSQRSATDRFSRPSQSDF-----------HQQGSAVPANNMLIGTSI---ID 411

  Fly   500 SRARFVFPLSFLVFNLFFWTFVY 522
            ..:|.:|||||..|||.:| .||
Zfish   412 KYSRILFPLSFGAFNLVYW-IVY 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:455710	139/537 (26%)
gabra6b	XP_002667403.3	LIC	33..433	CDD:455710	130/498 (26%)
		LGIC_ECD_GABAAR_A6	41..238	CDD:349840	54/226 (24%)
		Cys-loop	155..169	CDD:349840	5/13 (38%)