Protein Alignment CG6927 and gabrg1

DIOPT Version :10

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_009305483.1
• Gene: gabrg1 / 556202
• ZFINID: ZDB-GENE-141215-66
• Length: 454
• Species: Danio rerio
• Alignment Length: 540
• Identity: 126/540 - (23%)
• Similarity: 215/540 - (39%)
• Gaps: 128/540 - (23%)

  Fly     3 WSLIISILLNCL-YASASALDED------------CPTLDDGDSLSQTQLLDRLTHGCRYDRLER 54
            | |:..:|..|: :..:.|.:||            .|.:.:.|   .|.:|::|..|  ||...|
Zfish    13 W-LLPGLLGVCMAFGPSKAEEEDYEDVPINKTWVLSPKVYESD---VTLILNKLLQG--YDNKLR 71

  Fly    55 PITYSETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRRQPILGE 119
            |    :.|.| |..:....|:..:..::..::::.|.......:.|.||.| |.|.|.   ::..
Zfish    72 P----DIGVR-PTVIETAVYVNSIGPVDPINMEYTIDIFFAQTWYDSRLKF-NSSMKL---LMLN 127

  Fly   120 EHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQH 184
            .::...:|:|..|..|.|.|....:|..:.|..:..:|.|:.:.|:.....|:|.|..||.||..
Zfish   128 SNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRLWSNGRVMYTLRLTINAECYLKLHNFPMDEHS 192

  Fly   185 CSTVLESWMYNTSELVLHWEQKRPITYDGALHLTEFVLQRSW-----------SNETVINADLSD 238
            |.....|:.|..:|:...| |:|.:         |...||.|           ::..|.|..
Zfish   193 CPLEFSSYGYPKNEIQYRW-QRRSV---------EVADQRYWRLYQFAFVGLRNSSDVANTQ--- 244

  Fly   239 LRHGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLT 303
                  :|.|..::....|:|.:|::.:..::|..:||.:||||||:..|..|.|.:||.:|:||
Zfish   245 ------SGEYVVMTIFFDLSRRMGYFTIQTYIPCSMIVVLSWVSFWINKDAVPARTSLGITTVLT 303

  Fly   304 FITLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIWRRKKSVPVKKLNSKHILKS 368
            ..||::...|:||||||:...:::...|.||.|.:::|:..::.....:::   ||..|.|..|
Zfish   304 MTTLSTISRKSLPKVSYVTAMDLFVSVCFIFTFAALMEYGTLHYFTSNRQN---KKTKSSHAQK- 364

  Fly   369 TLSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQVLDQQRTSRVV 433
               |:::..|        .||:|.:           .||....:              :......
Zfish   365 ---PSMVNIR--------PGTSLLQ-----------MNNIAPYH--------------EDDDYAY 393

  Fly   434 QKMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNRTESAGHQEEIDLSGWTTLTPQEIAMWI 498
            :.:|.....|.|......:| ||                             |...........|
Zfish   394 ECLDGKDCTSFFCCFDDCRS-GA-----------------------------WRENRMHVHVSKI 428

  Fly   499 DSRARFVFPLSFLVFNLFFW 518
            ||.:|..||.:|.:|||.:|
Zfish   429 DSYSRIFFPTAFGLFNLVYW 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:455710	126/540 (23%)
gabrg1	XP_009305483.1	LIC	58..451	CDD:455710	116/491 (24%)
		LGIC_ECD_GABAAR_G	79..260	CDD:349801	43/203 (21%)
		Cys-loop	179..193	CDD:349801	7/13 (54%)