DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6927 and ort

DIOPT Version :9

Sequence 1:	NP_572194.1	Gene:	CG6927 / 31419	FlyBaseID:	FBgn0029733	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_524406.1	Gene:	ort / 45910	FlyBaseID:	FBgn0003011	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	118/516 - (22%)
Similarity:	206/516 - (39%)	Gaps:	113/516 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 RYDRLERPITYSETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNF-RNVSPK 111
            |||::..|   .:.||  |..||....:..:.:::.:.:.:.........:.|.||.. .|::.:
  Fly    39 RYDKMRPP---KKEGQ--PTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQE 98

  Fly   112 RRQPILGEEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLK 176
            .|  :|..:.|:| :|.|..|..|.:..:...:|..:....:..|.|::...::...|.|.:|..
  Fly    99 YR--LLEVDWLKN-MWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFA 160

  Fly   177 KFPFDEQHCSTVLESWMYNTSELVLHWEQKRPITYDGALHLTEFVLQRSWSNETVINADLSDLRH 241
            .:|.|.|.|...:||..:.|.:|:..|:...|:..|..:.|.:..|.|   |||   ||.:.:..
  Fly   161 IYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENIELPQVALIR---NET---ADCTQVYS 219

  Fly   242 GAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFIT 306
               .||::.|.....|.|.:.:|:.:.::|:.:||.:||||||::.:.||.|:|||.::|||..|
  Fly   220 ---TGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLST 281

  Fly   307 LASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIWRRKKSVPVKKLNSKHILKSTLS 371
            ..:....:||.|||:|..:.:...||:|:|.:::|:..:|.:           |:...|.|....
  Fly   282 QHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIV-----------LSDTPIPKPMAY 335

  Fly   372 PNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQVLDQQRTSRVVQKM 436
            |          .:..:|....|..:....||:.           :|..:     ||.|...:...
  Fly   336 P----------PKPVAGDGPKKEGEGAPPGGSN-----------STASK-----QQATMLPLADE 374

  Fly   437 DVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNR---TESAGHQEEIDLSG-W----------- 486
            .:..:|..|..|                  |.|.|   |.....:..:|..| |
  Fly   375 KIEKIEKIFDEM------------------TKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILT 421

  Fly   487 ---------------------TTLTPQE----IAMWIDSRARFVFPLSFLVFNLFFWTFVY 522
                                 ..|||.:    .|::||..:|.:||..|...|..:|...|
  Fly   422 PTIAPPPPPPQPAAPEPELPKPKLTPAQERLKRAIYIDRSSRVLFPALFASLNGIYWCVFY 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:273305	117/512 (23%)
		Neur_chan_LBD	36..259	CDD:280998	50/211 (24%)
		Neur_chan_memb	270..518	CDD:280999	64/287 (22%)
ort	NP_524406.1	LIC	31..481	CDD:273305	117/513 (23%)
		Neur_chan_LBD	38..235	CDD:280998	50/212 (24%)
		Neur_chan_memb	243..>334	CDD:280999	34/101 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5256
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.860