Protein Alignment CG6927 and nAChRbeta2

DIOPT Version :9

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_524483.1
• Gene: nAChRbeta2 / 42920
• FlyBaseID: FBgn0004118
• Length: 519
• Species: Drosophila melanogaster
• Alignment Length: 586
• Identity: 121/586 - (20%)
• Similarity: 203/586 - (34%)
• Gaps: 180/586 - (30%)

  Fly     3 WSLIISILLNCLYASASAL----DEDCPTLDDGDSLSQTQLLDRLTHGCRYDRLERPITYSETGQ 63
            |||:...||..|..|.:.:    :.|...|.| |.||            .|:||.||:.  ...:
  Fly     4 WSLLCVFLLVPLANSTAPISFEANPDTKRLYD-DLLS------------NYNRLIRPVV--NNTE 53

  Fly    64 RLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKR----RQPILGEEHLRN 124
            .|.|.:.::.......||:...:...::  ::.|:.|.:|.:   .|:.    .|..:..||
  Fly    54 TLTVWLGLKLSQLIEVNLKNQVMTTNLW--VKQRWFDYKLRW---DPEEYGGVEQLYVPSEH--- 110

  Fly   125 SLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATL----------------YCWL 173
             :|:|.|.|.|..|    |..|..::|              ||||                .|.:
  Fly   111 -IWVPDIVLYNNWD----GNYEVTLMT--------------KATLKYTGEVFWEPPAIYKSSCEM 156

  Fly   174 NLKKFPFDEQHCSTVLESWMYNTSELVL-HWEQKRPITYDGA------LHLTEFVLQRSW----- 226
            |::.||:|||.|.....||.||.:::.| |.:|     ..|:      :.||||.|...|
  Fly   157 NVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQ-----IPGSNLVQVGIDLTEFYLSVEWDILEV 216

  Fly   227 ---SNETVINADLSDLRHGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQAD 288
               .||......|..         :|.::|.:.:.|...||.::..:|.:.:..::.:.|:|.:|
  Fly   217 PATKNEEYYPDTLEP---------FSDITFKLTMRRKTLFYTVNLIVPCVALTFLTVLVFYLPSD 272

  Fly   289 QAPPRITLGTSTLLT----FITLAS----------AQGKTLPKVSYIKVSEVWFLGCTIFIFGSM 339
            .. .::||..|.|::    |:.||.          ..||.|.....:....||...|.:     .
  Fly   273 SG-EKVTLCISILVSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVSLSVWTTVCVL-----N 331

  Fly   340 VEFAFVNTIWRRKKSVPVKKLNSKHILKSTLSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAG 404
            :.|...:|   ...|..|:|| ..|.:...:   ::||..:........|..:           |
  Fly   332 IHFRSPST---HNMSPLVRKL-FLHFMPKLM---MMRRTQYTLPDYDDSTPSN-----------G 378

  Fly   405 FNNYLTVNLPITTIKEGQVLDQQRTSRVVQKMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNN 469
            :.|.:.|...|:                      :|......|...|...|..::..|...:..|
  Fly   379 YTNEIDVRDSIS----------------------DFPSEFKDSQDGAYDNGMQNSVDSDNVIPRN 421

  Fly   470 NRTE----------SAGHQEEIDLSGWTTLTPQEIAMWIDSRARFVFPLSFLVFNLFFWTF-VYC 523
            ...|          .|.|.::.|...      :.:..|     :||   |.::...|.|.| :.|
  Fly   422 LTPEVLQALRAVRFIAQHIKDADKDN------EIVEDW-----KFV---SMVLDRFFLWLFTLSC 472

  Fly   524 I 524
            :
  Fly   473 V 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:273305	119/579 (21%)
		Neur_chan_LBD	36..259	CDD:280998	56/257 (22%)
		Neur_chan_memb	270..518	CDD:280999	46/271 (17%)
nAChRbeta2	NP_524483.1	LIC	9..479	CDD:273305	118/581 (20%)
		LGIC_ECD_nAChR_proto_alpha-like	29..247	CDD:349832	63/273 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447275
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030