Protein Alignment CG6927 and Gabra5

DIOPT Version :10

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_058991.2
• Gene: Gabra5 / 29707
• RGDID: 61859
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 495
• Identity: 120/495 - (24%)
• Similarity: 207/495 - (41%)
• Gaps: 110/495 - (22%)

  Fly    37 TQLLDRLTHGCRYDRLERPITYSETGQRLP---VDVYMRAYIYFMQNLEAHDLQFKIYALLQMRY 98
            |::||.|..|  ||...||    ..|:|:.   .|:|:.::    ..:...::::.|....:..:
  Rat    50 TRILDGLLDG--YDNRLRP----GLGERITQVRTDIYVTSF----GPVSDTEMEYTIDVFFRQSW 104

  Fly    99 LDPRLNFRNVSPKRRQPILGEEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSN 163
            .|.||.|:  .|.:|.|:  ...|.:.:|.|..|..|.:.|....:|..:.|..:..|||::.:.
  Rat   105 KDERLRFK--GPMQRLPL--NNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTM 165

  Fly   164 RIKATLYCWLNLKKFPFDEQHCSTVLESWMYNTSELVLHW---EQKRPITYDGALHLTEFVLQRS 225
            |:..:..|.:.|:.||.|...|.....|:.|..||:|..|   ..|..:..:....|.::.|.
  Rat   166 RLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLM-- 228

  Fly   226 WSNETVINADLSDLRHGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQA 290
              .:||...::|     ...|.|:.::...||.|.:|::::..:||.::.|.:|.|||||..:..
  Rat   229 --GQTVGTENIS-----TSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESV 286

  Fly   291 PPRITLGTSTLLTFITLASAQGKTLPKVSYIKVSEVWFLG-CTIFIFGSMVEFAFVNTI------ 348
            |.|...|.:|:||..||:.:...:||||:|....: ||:. |..|:|.:::|||.||..
  Rat   287 PARTVFGVTTVLTMTTLSISARNSLPKVAYATAMD-WFIAVCYAFVFSALIEFATVNYFTKRGWA 350

  Fly   349 WRRKKSVPVKKLNSKHILKSTLSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNL 413
            |..||::...|:..|.      ...:|.:.::|.:   :|...|..                 |:
  Rat   351 WDGKKALEAAKIKKKE------RELILNKSTNAFT---TGKLTHPP-----------------NI 389

  Fly   414 PITTIKEGQVLDQQRTSRVVQKMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNRTESAGHQ 478
            |                          .|...|..|:|..|.:|.|  |.:..:.:.:|.::..:
  Rat   390 P--------------------------KEQLPGGTGNAVGTASIRA--SEEKTSESKKTYNSISK 426

  Fly   479 EEIDLSGWTTLTPQEIAMWIDSRARFVFPLSFLVFNLFFW 518
                               ||..:|.|||:.|..|||.:|
  Rat   427 -------------------IDKMSRIVFPILFGTFNLVYW 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:455710	120/495 (24%)
Gabra5	NP_058991.2	LIC	15..450	CDD:455710	120/495 (24%)
		LGIC_ECD_GABAAR_A5	58..256	CDD:349839	51/220 (23%)
		Cys-loop	173..187	CDD:349839	5/13 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	382..414		11/76 (14%)