Protein Alignment CG6927 and Gabra1

DIOPT Version :9

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_899155.1
• Gene: Gabra1 / 29705
• RGDID: 61855
• Length: 455
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 131/540 - (24%)
• Similarity: 213/540 - (39%)
• Gaps: 139/540 - (25%)

  Fly     3 WSLIISILLNCLYASASALDEDCPTLDDGDSLSQTQLLDRLTHGCRYDRLERPITYSETGQR--- 64
            |:||:|.|....|...|. ||    |.|..::. |::||||..|  ||...||    ..|:|
  Rat    14 WTLILSTLSGRSYGQPSQ-DE----LKDNTTVF-TRILDRLLDG--YDNRLRP----GLGERVTE 66

  Fly    65 LPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRRQPILGEEHLRNSLWMP 129
            :..|:::.::    ..:..||:::.|....:..:.|.||.|:......|...|    :.:.:|.|
  Rat    67 VKTDIFVTSF----GPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNL----MASKIWTP 123

  Fly   130 HIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQHCSTVLESWMY 194
            ..|..|.:.|....:|..:.|..|:.|||::.:.|:.....|.::|:.||.|...|.....|:.|
  Rat   124 DTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAY 188

  Fly   195 NTSELVLHW--EQKRPITY--DGALHLTEFVLQRSWSNETVINADLSDLRHGAFAGNYSSLSFTV 255
            ..:|:|..|  |..|.:..  ||: .|.::.|.....:..::.:.         .|.|..::...
  Rat   189 TRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIVQSS---------TGEYVVMTTHF 243

  Fly   256 HLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFITLASAQGKTLPKVSY 320
            ||.|.:|::::..:||.::.|.:|.|||||..:..|.|...|.:|:||..||:.:...:||||:|
  Rat   244 HLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAY 308

  Fly   321 IKVSEVWFLG-CTIFIFGSMVEFAFVNTI------WRRKKSVP----------VKKLNSKHILKS 368
            ....: ||:. |..|:|.:::|||.||..      |..|..||          :||.|:.....:
  Rat   309 ATAMD-WFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTAT 372

  Fly   369 TLSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQVLDQQRTSRVV 433
            :.:|||.|                     |..|.|......|:. |.....|.:..:.::|...|
  Rat   373 SYTPNLAR---------------------GDPGLATIAKSATIE-PKEVKPETKPPEPKKTFNSV 415

  Fly   434 QKMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNRTESAGHQEEIDLSGWTTLTPQEIAMWI 498
            .|                                                              |
  Rat   416 SK--------------------------------------------------------------I 418

  Fly   499 DSRARFVFPLSFLVFNLFFW 518
            |..:|..|||.|.:|||.:|
  Rat   419 DRLSRIAFPLLFGIFNLVYW 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:273305	131/540 (24%)
		Neur_chan_LBD	36..259	CDD:280998	55/229 (24%)
		Neur_chan_memb	270..518	CDD:280999	62/264 (23%)
Gabra1	NP_899155.1	LIC	7..441	CDD:273305	131/540 (24%)
		LGIC_ECD_GABAAR_A1	55..248	CDD:349835	47/214 (22%)
		Cys-loop	165..179	CDD:349835	5/13 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810