Protein Alignment CG6927 and GLRA1

DIOPT Version :10

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_047273061.1
• Gene: GLRA1 / 2741
• HGNCID: 4326
• Length: 465
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 146/499 - (29%)
• Similarity: 232/499 - (46%)
• Gaps: 102/499 - (20%)

  Fly    34 LSQTQLLDRL---THGCRYDRLERPITYSETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQ 95
            :|.:..||:|   |.|  ||...||     ..:..||:|....:|....::....:.:::...|:
Human    52 MSPSDFLDKLMGRTSG--YDARIRP-----NFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLR 109

  Fly    96 MRYLDPRLNFRNVSPKRRQPILGEEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVI 160
            .::.||||.: |..|.....:  :..:.:|:|.|.:|.|||:.:....:|..:.|..||.:|.|:
Human   110 QQWNDPRLAY-NEYPDDSLDL--DPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVL 171

  Fly   161 VSNRIKATLYCWLNLKKFPFDEQHCSTVLESWMYNTSELVLHWEQKRPITYDGALHLTEFVLQRS 225
            .|.||..||.|.::||.||.|.|.|...|||:.|..::|:..|:::..:.....|.|.:|:|:..
Human   172 YSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEE 236

  Fly   226 WSNETVINADLSDLRHGA---FAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQA 287
                       .|||:..   ..|.::.:....||.|.:|:||:..::||:|||.:||:|||:..
Human   237 -----------KDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINM 290

  Fly   288 DQAPPRITLGTSTLLTFITLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIWRRK 352
            |.||.|:.||.:|:||..|.:|....:||||||:|..::|...|.:|:|.:::|:|.||.:.|:.
Human   291 DAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQH 355

  Fly   353 KSVPVKKLNSKHILKSTLSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITT 417
            |                   .|||.|...|.        ||..:.|
Human   356 K-------------------ELLRFRRKRRH--------HKEDEAG------------------- 374

  Fly   418 IKEGQVLDQQRTSRVVQKMDVNFVESAFGSMGSA--QSTGAISAASSSQTLTNNNRTESAGHQEE 480
              ||:               .||  ||:| ||.|  |:...||...::.:.|.|.....:...||
Human   375 --EGR---------------FNF--SAYG-MGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEE 419

  Fly   481 IDLSGWTTLTPQEIAMWIDSRARFVFPLSFLVFNLFFWTFVYCI 524
            :     ..|..|. |..||..:|..||::||:||:|:| .:|.|
Human   420 M-----RKLFIQR-AKKIDKISRIGFPMAFLIFNMFYW-IIYKI 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:455710	144/493 (29%)
GLRA1	XP_047273061.1	LIC	24..454	CDD:273305	144/495 (29%)