Protein Alignment CG6927 and GABRR2

DIOPT Version :9

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_002034.3
• Gene: GABRR2 / 2570
• HGNCID: 4091
• Length: 465
• Species: Homo sapiens
• Alignment Length: 462
• Identity: 113/462 - (24%)
• Similarity: 212/462 - (45%)
• Gaps: 77/462 - (16%)

  Fly    62 GQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRRQPILGEEHLRNSL 126
            |..:||.|.::  :..:.::...|:.|.:...|:..:.|.||.|.:.|.|   .:..:..|...:
Human    74 GPAIPVGVDVQ--VESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNK---SMTFDGRLVKKI 133

  Fly   127 WMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQHCSTVLES 191
            |:|.:|..:.:.|.....|..:|:..:.|||.|:.|.||..|..|.::...||.|.|.||..|||
Human   134 WVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELES 198

  Fly   192 WMYNTSELVLHWEQ-KRPITYDGALHLTEFVLQRSWSNETVINADLSDLRHGAFAGNYSSLSFTV 255
            :.|...:|:|:|:. ...:..|..:.|::|::|:..:.        |.|...:..|.|:.|....
Human   199 YAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTT--------SRLAFYSSTGWYNRLYINF 255

  Fly   256 HLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFITLASAQGKTLPKVSY 320
            .|.|.:.|:|:..:.|:.|:|.:||||||:.....|.|::||.:|:||..|:.:....::|:|||
Human   256 TLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRVSY 320

  Fly   321 IKVSEVWFLGCTIFIFGSMVEFAFVN---TIWRRKKSVPVKKLNSKHILKSTLSPNLLRRRSHAR 382
            :|..:::.....:|:|.|::|:|.||   |:..||:    :||..|......:        .|::
Human   321 VKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKE----RKLREKFPCMCGM--------LHSK 373

  Fly   383 SRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQVLDQQRTSRVVQKMDVNFVESAFGS 447
            :....|:  :..::..||.|...::.||              :::|..::|..:.::      |.
Human   374 TMMLDGS--YSESEANSLAGYPRSHILT--------------EEERQDKIVVHLGLS------GE 416

  Fly   448 MGSAQSTGAISAASSSQTLTNNNRTESAGHQEEIDLSGWTTLTPQEIAMWIDSRARFVFPLSFLV 512
            ..:|:..|.:...:..:...|.:.                          ||..:|.:||.|::.
Human   417 ANAARKKGLLKGQTGFRIFQNTHA--------------------------IDKYSRLIFPASYIF 455

  Fly   513 FNLFFWT 519
            |||.:|:
Human   456 FNLIYWS 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:273305	113/462 (24%)
		Neur_chan_LBD	36..259	CDD:280998	52/197 (26%)
		Neur_chan_memb	270..518	CDD:280999	57/250 (23%)
GABRR2	NP_002034.3	Neur_chan_LBD	51..464	CDD:332142	113/462 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810