Protein Alignment CG6927 and GABRG3

DIOPT Version :9

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_011519732.1
• Gene: GABRG3 / 2567
• HGNCID: 4088
• Length: 473
• Species: Homo sapiens
• Alignment Length: 549
• Identity: 127/549 - (23%)
• Similarity: 224/549 - (40%)
• Gaps: 113/549 - (20%)

  Fly     5 LIISILLNCLYASASALDED-------------CPTLDDGDSLSQTQLLDRLTHGCRYDRLERPI 56
            |::..|.:.|:|.:..::||             .|...|.|   .|.:|::|..  .||:..||
Human     6 LLLLCLFSGLHARSRKVEEDEYEDSSSNQKWVLAPKSQDTD---VTLILNKLLR--EYDKKLRP- 64

  Fly    57 TYSETGQR---LPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRRQPILG 118
               :.|.:   :.||:|:.:    :..:.:.:::::|.......:.|.||.|.:.     ..||.
Human    65 ---DIGIKPTVIDVDIYVNS----IGPVSSINMEYQIDIFFAQTWTDSRLRFNST-----MKILT 117

  Fly   119 -EEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDE 182
             ..::...:|:|.....|.:.:....:|..:.|..|..||.::.:.|:.....|.|.|..||.||
Human   118 LNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDE 182

  Fly   183 QHCSTVLESWMYNTSELVLHWEQKRPITYDGALHLTEFVLQRSWSNETVINADLSDLRH-----G 242
            ..|..:..|:.|...|::..|.:          :..|...|:||   .:...|...||:     .
Human   183 HSCPLIFSSYGYPKEEMIYRWRK----------NSVEAADQKSW---RLYQFDFMGLRNTTEIVT 234

  Fly   243 AFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFITL 307
            ..||:|..::....|:|.:|::.:..::|.:|.|.:||||||::.|..|.|..||.:|:||..||
Human   235 TSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTL 299

  Fly   308 ASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIWRRKKSVPVKKLNSKHILKSTLSP 372
            ::...|:||:|||:...:::...|.:|:|.:::|:|.:|.....:|....||..      |.|.|
Human   300 STIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTT------SLLHP 358

  Fly   373 NLLR---RRSHARSRSFSGTALHKTADTGSLGGAGFNNY--LTVNLPIT---TIKEGQVLDQQRT 429
            :..|   .|...::.|..               ....||  |.:..|.|   |:.......:...
Human   359 DSSRWIPERISLQAPSVR---------------IALQNYSLLDMRPPPTAMITLNNSVYWQEFED 408

  Fly   430 SRVVQKMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNRTESAGHQEEIDLSGWTTLTPQEI 494
            :.|.:.:|....:|.|..                              .||.....|........
Human   409 TCVYECLDGKDCQSFFCC------------------------------YEECKSGSWRKGRIHID 443

  Fly   495 AMWIDSRARFVFPLSFLVFNLFFWT-FVY 522
            .:.:||.:|..||.|||:|||.:|. ::|
Human   444 ILELDSYSRVFFPTSFLLFNLVYWVGYLY 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:273305	126/545 (23%)
		Neur_chan_LBD	36..259	CDD:280998	50/231 (22%)
		Neur_chan_memb	270..518	CDD:280999	64/255 (25%)
GABRG3	XP_011519732.1	Neur_chan_LBD	48..253	CDD:280998	51/232 (22%)
		LIC	50..470	CDD:273305	116/498 (23%)
		Neur_chan_memb	260..467	CDD:280999	64/257 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810