Protein Alignment CG6927 and GABRB2

DIOPT Version :9

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001358656.1
• Gene: GABRB2 / 2561
• HGNCID: 4082
• Length: 512
• Species: Homo sapiens
• Alignment Length: 555
• Identity: 140/555 - (25%)
• Similarity: 253/555 - (45%)
• Gaps: 95/555 - (17%)

  Fly     3 WSLIISILLNCLYASASALDEDCPTLDDGDSLSQT-QLLDRLTHGCRYDRLERPITYSETGQRLP 66
            ||..:.|...|           ..:::|..::|.. :.:|||..|  ||...||    :.|.. |
Human    13 WSFPLIIAAVC-----------AQSVNDPSNMSLVKETVDRLLKG--YDIRLRP----DFGGP-P 59

  Fly    67 VDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRRQPILGEEHLRNSLWMPHI 131
            |.|.|...|..:..:...::.:.:....|..:.|.||:: ||.|..   :..:..:.:.||:|..
Human    60 VAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSY-NVIPLN---LTLDNRVADQLWVPDT 120

  Fly   132 FLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQHCSTVLESWMYNT 196
            :..|::.|.:.|:|.|:.:..:.|||||:...||..|..|.::|:::|.|||:|:..:||:.|.|
Human   121 YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTT 185

  Fly   197 SELVLHWE-QKRPITYDGALHLTEFVLQRSWSNETVINADLSDLRHGAFAGNYSSLSFTVHLTRV 260
            .::..:|. ....:|....:.|.:|         ::::..|...:.....|:|..||.:..|.|.
Human   186 DDIEFYWRGDDNAVTGVTKIELPQF---------SIVDYKLITKKVVFSTGSYPRLSLSFKLKRN 241

  Fly   261 VGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFITLASAQGKTLPKVSYIKVSE 325
            :|::::..::||:||..:||||||:..|.:..|:.||.:|:||..|:.:...:||||:.|:|..:
Human   242 IGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAID 306

  Fly   326 VWFLGCTIFIFGSMVEFAFVNTIW------RRKKSVPVKKLNSKHILKSTLSPNLLRRRSHARSR 384
            ::.:||.:|:|.:::|:|.||.|:      |:||:  .:|..|.:..|..|..|.:..:...:
Human   307 MYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKA--AEKAASANNEKMRLDVNKIFYKDIKQ-- 367

  Fly   385 SFSGTALHKTAD-TGSLG------GAGFNNYLT---VNLPITTIKEGQVLDQQRTSRVVQKMDVN 439
              :||......| ||:|.      ...|:.|..   .|:.::|:   ::.::..||..|.
Human   368 --NGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTL---EIKNEMATSEAVM----- 422

  Fly   440 FVESAFGSMGSAQSTGAISAASSSQ-------------------TLTNNNRTESAGHQEEIDLSG 485
                   .:|..:||.....|||.|                   .....:|......|.:|.:..
Human   423 -------GLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPD 480

  Fly   486 WTTLTPQEIAMWIDSRARFVFPLSFLVFNLFFWTF 520
            .|.:..      ||..:|..||:.|..||:.:|.:
Human   481 LTDVNA------IDRWSRIFFPVVFSFFNIVYWLY 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:273305	140/553 (25%)
		Neur_chan_LBD	36..259	CDD:280998	58/224 (26%)
		Neur_chan_memb	270..518	CDD:280999	73/282 (26%)
GABRB2	NP_001358656.1	LIC	9..510	CDD:273305	140/555 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910