DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6927 and Gabrb1

DIOPT Version :9

Sequence 1:	NP_572194.1	Gene:	CG6927 / 31419	FlyBaseID:	FBgn0029733	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_037088.1	Gene:	Gabrb1 / 25450	RGDID:	2649	Length:	474	Species:	Rattus norvegicus

Alignment Length:	493	Identity:	123/493 - (24%)
Similarity:	226/493 - (45%)	Gaps:	70/493 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 QLLDRLTHGCRYDRLERPITYSETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPR 102
            :.:|||..|  ||...||    :.|.. ||||.||..:..:..:...::.:.:....|..:.|.|
  Rat    39 ETVDRLLKG--YDIRLRP----DFGGP-PVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKR 96

  Fly   103 LNFRNVSPKRRQPILGEEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKA 167
            |::..:...    :..:..:.:.||:|..:..|::.|.:.|:|.|:.:..:.|||||:...||..
  Rat    97 LSYSGIPLN----LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITT 157

  Fly   168 TLYCWLNLKKFPFDEQHCSTVLESWMYNTSELVLHWE-QKRPITYDGALHLTEFVLQRSWSNETV 231
            |..|.::|:::|.|||:|:..:||:.|.|.::..:|. .:..:|....:.|.:|         ::
  Rat   158 TAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQF---------SI 213

  Fly   232 INADLSDLRHGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITL 296
            ::..:...:.....|.|..||.:..|.|.:|::::..::||.||..:||||||:..|.:..|:.|
  Rat   214 VDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVAL 278

  Fly   297 GTSTLLTFITLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIWRRKKSVPVKKLN 361
            |.:|:||..|:::...:||||:.|:|..:::.:||.:|:|.:::|:||||.|:..|.  |.||..
  Rat   279 GITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKG--PQKKGA 341

  Fly   362 SKHIL----KSTLSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQ 422
            ||...    |:.|..|.::..:|                         .|.|...|.|.....|.
  Rat   342 SKQDQSANEKNKLEMNKVQVDAH-------------------------GNILLSTLEIRNETSGS 381

  Fly   423 -----VLDQQRTSRVVQKMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNRTESAGHQEEID 482
                 |.|.:.|........:.:.:    .:.|.:..|   .......:....|......|.::.
  Rat   382 EVLTGVSDPKATMYSYDSASIQYRK----PLSSREGFG---RGLDRHGVPGKGRIRRRASQLKVK 439

  Fly   483 LSGWTTLTPQEIAMWIDSRARFVFPLSFLVFNLFFWTF 520
            :...|.:..      ||..:|..||::|.:||:.:|.:
  Rat   440 IPDLTDVNS------IDKWSRMFFPITFSLFNVVYWLY 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:273305	123/491 (25%)
		Neur_chan_LBD	36..259	CDD:280998	55/221 (25%)
		Neur_chan_memb	270..518	CDD:280999	65/256 (25%)
Gabrb1	NP_037088.1	LIC	9..472	CDD:273305	123/493 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810