Protein Alignment CG6927 and Gabrr3

DIOPT Version :9

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_620252.1
• Gene: Gabrr3 / 192258
• RGDID: 621564
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 132/537 - (24%)
• Similarity: 242/537 - (45%)
• Gaps: 103/537 - (19%)

  Fly     3 WSLIISILLNCLYASASALDE---DCPTLDDGDSLSQTQL------------LDRLTHGCRYDRL 52
            |....:.....|...|||:.|   .|.:......:.:|::            .::|.|...:|..
  Rat     6 WLAFFTYTWITLMLDASAVKEPHQQCLSSPKQTRIRETRMRKDDLTKVWPLKREQLLHIEDHDFS 70

  Fly    53 ERPITYSETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRRQPIL 117
            .||   ...|..:||.:.::  :..:.::...::.|.:...|:..:.|.||:|.:.:.|   .:.
  Rat    71 TRP---GFGGSPVPVGIDVQ--VESIDSISEVNMDFTMTFYLRHYWKDERLSFPSTTNK---SMT 127

  Fly   118 GEEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDE 182
            .:..|...:|:|.||..:.:.|.|...|.::|:..:.|||.|:.|.||..:..|:::..:||.|.
  Rat   128 FDRRLIQKIWVPDIFFVHSKRSFIHDTTVENIMLRVHPDGNVLFSLRITVSAMCFMDFSRFPLDT 192

  Fly   183 QHCSTVLESWMYNTSELVLHWEQ-KRPITYDGALHLTEFVLQRSWSNETVINADLSDLRHGAFAG 246
            |:||..|||:.||..:|:|:|:. .:.:..:..:.|::|.::...::        |.|...:..|
  Rat   193 QNCSLELESYAYNEEDLMLYWKHGNKSLNTEEHISLSQFFIEEFSAS--------SGLAFYSSTG 249

  Fly   247 NYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFITLASAQ 311
            .|..|.....|.|.:.|:::..:.|:||:|.:||||||:.....|.|::||.:|:||..|:.:..
  Rat   250 WYYRLFINFVLRRHIFFFVLQTYFPAMLMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIVTGV 314

  Fly   312 GKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTI-----WRRKKSVPVKKLNSKHILKSTLS 371
            ..::|:|||:|..:|:....::|:|.|::|:|.||.:     |        |:||.:..:....:
  Rat   315 SASMPQVSYVKAVDVYMWVSSLFVFLSVIEYAAVNYLTTVEEW--------KQLNRRGKISGMYN 371

  Fly   372 PNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQVLDQQRTSRVVQKM 436
            .:.:      ::.:|.| ..|                           :|:. |..:||
  Rat   372 IDAV------QAMAFDG-CYH---------------------------DGET-DVDQTS------ 395

  Fly   437 DVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNRTESAGHQEEIDLSGWTTLTPQEIAMWIDSR 501
              .|:.|...|| ..:.||: ..|.|||.    .|....|:...|.|         |....||:.
  Rat   396 --FFLHSEEDSM-RTKFTGS-PCADSSQI----KRKSLGGNVGRIIL---------ENNHVIDTY 443

  Fly   502 ARFVFPLSFLVFNLFFW 518
            :|.|||:.:::||||:|
  Rat   444 SRIVFPVVYIIFNLFYW 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:273305	132/537 (25%)
		Neur_chan_LBD	36..259	CDD:280998	55/235 (23%)
		Neur_chan_memb	270..518	CDD:280999	67/252 (27%)
Gabrr3	NP_620252.1	LIC	58..463	CDD:273305	124/485 (26%)
		LGIC_ECD	79..264	CDD:355788	49/197 (25%)
		Cys-loop	181..195	CDD:349787	5/13 (38%)
		Interaction with SQSTM1. /evidence=ECO:0000269|PubMed:12431995	344..445		32/166 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810