Protein Alignment CG6927 and unc-49

DIOPT Version :10

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001022785.1
• Gene: unc-49 / 176472
• WormBaseID: WBGene00006784
• Length: 506
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 152/545 - (27%)
• Similarity: 245/545 - (44%)
• Gaps: 90/545 - (16%)

  Fly     3 WSLIISILLN-CLYASASALDEDCPTLDDGDSLSQTQL----LDRLTHGCRYDRLERPITYSETG 62
            ::||:.:..: ||:...:         .|.||...|||    |||||:...||:..|| .|.|.
 Worm     5 FTLIVLLSAHLCLHVVVT---------QDEDSHINTQLLSSVLDRLTNRTTYDKRLRP-RYGEK- 58

  Fly    63 QRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRRQPI----LGEEHLR 123
               ||||.:..::..:..:...|:.|.:...::..:.||||.|.::.....:.|    :|.::|
 Worm    59 ---PVDVGITIHVSSISAVSEVDMDFTLDFYMRQTWQDPRLAFGSLDLGLSKEIDSLTVGVDYL- 119

  Fly   124 NSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQHCSTV 188
            :.||.|..|..||:.|.....|..:....|..||||..|.|:..|..|.::||.||.|.|||...
 Worm   120 DRLWKPDTFFPNEKKSFFHLATTHNSFLRIEGDGTVYTSQRLTVTATCPMDLKLFPMDSQHCKLE 184

  Fly   189 LESWMYNTSELVLHWEQKR------PITYDGALHLTEFVLQRSWSNETVINADLSDLRHGAFAGN 247
            :||:.|.|.::..:|.:||      .:.:| ...|.:|.....:.|.|  .|:.|       :|.
 Worm   185 IESYGYETKDIDYYWGKKRTDLEITAVKFD-TFQLPQFQPTLYFVNTT--KAETS-------SGK 239

  Fly   248 YSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFITLASAQG 312
            |..|:..|.|.|.:|||.|:..:||:|||.||||||||..:.:|.|:.||.:|:||..||.:...
 Worm   240 YVRLALEVILVRNMGFYTMNIVIPSILIVTISWVSFWLNREASPARVGLGVTTVLTMTTLITTTN 304

  Fly   313 KTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTI--------WRRKKSVPVKKLNSKHILKST 369
            .::|||||:|..:|:...|.:.:|.|::|:|.|:.:        .:|:|:...::.|...:..:
 Worm   305 NSMPKVSYVKGLDVFLNFCFVMVFASLLEYAIVSYMNKRLVLRREKRRKAAEQQQRNEMPMFNA- 368

  Fly   370 LSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEG---QVLDQQRTSR 431
             ||......|:..:.....:...|:.....|..||.|:.:.   |:..|.|.   :.:...:..|
 Worm   369 -SPKAANNNSYEMTLMSQNSTPAKSYVQADLYFAGHNSSMN---PLMEIPENCDCRTIPMMQHPR 429

  Fly   432 VVQKMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNRTESAGHQEEIDLSGWTTLTPQEIAM 496
            :|.........:.|.....|..|..                           ..|   ||.:
 Worm   430 LVTDGAHTLWPAPFARPKKASKTCC---------------------------QRW---TPAK--- 461

  Fly   497 WIDSRARFVFPLSFLVFNLFFWTFV 521
             ||..:|:.|||||.:||:.:|.::
 Worm   462 -IDKLSRYGFPLSFSIFNIVYWLYM 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:455710	152/542 (28%)
unc-49	NP_001022785.1	LIC	37..484	CDD:455710	142/501 (28%)