Protein Alignment CG6927 and Glrb

DIOPT Version :9

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_036018791.1
• Gene: Glrb / 14658
• MGIID: 95751
• Length: 530
• Species: Mus musculus
• Alignment Length: 525
• Identity: 142/525 - (27%)
• Similarity: 233/525 - (44%)
• Gaps: 102/525 - (19%)

  Fly    35 SQTQLLDRLTHGCRYDRLERPITYSETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYL 99
            |.:.:|:||.  ..||...||     ..:.:||||.:..:|....:::...:.:::...|:.::.
Mouse    65 STSNILNRLL--VSYDPRIRP-----NFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWN 122

  Fly   100 DPRL----NFRNVSPKRRQPILGEEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVI 160
            ||||    :||........|.     :...||.|.:|.|||:.::...:|:::||..|..||.|:
Mouse   123 DPRLKLPSDFRGSDALTVDPT-----MYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVL 182

  Fly   161 VSNRIKATLYCWLNLKKFPFDEQHCSTVLESWMYNTSELVLHWEQKRPITYDGALHLTEFVLQRS 225
            ||.|:..||.|.|:|..||.|.|.|...|||:.|.|.:|...|:...|:..: .:.|.:|.:::
Mouse   183 VSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLE-KIALPQFDIKK- 245

  Fly   226 WSNETVINADLSDLRHG------AFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFW 284
                       .|:.:|      ...|.|:.:.....|.|.||||:|..:.|::|||.:||:|||
Mouse   246 -----------EDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFW 299

  Fly   285 LQADQAPPRITLGTSTLLTFITLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIW 349
            :..|.:..|:.||..::|:..:..:.....||||||:|..:||.:.|.:|.|.|:||:|.|..:.
Mouse   300 INPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVML 364

  Fly   350 RRKKSVPVKKLNSKHILKSTLSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVN-- 412
            ...|.|..:|                     ||      .|..:.|| |..|.|...|  |||
Mouse   365 NNPKRVEAEK---------------------AR------IAKAEQAD-GKGGNAAKKN--TVNGT 399

  Fly   413 ---LPITTIKEGQVLDQQRTSRVVQKMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNRTES 474
               :.|:|::|..::.||    :..::|....::....:|   .|......:|...|.:|:.:..
Mouse   400 GTPVHISTLQELPMVCQQ----ITYQLDGWPTDTLTTQVG---ETRCKKVCTSKSDLRSNDFSIV 457

  Fly   475 AGHQEEIDLSGWTTL-TPQEI------------------------AMWIDSRARFVFPLSFLVFN 514
            .....:.:||.:... .|.|:                        |..||..||.:||..||.||
Mouse   458 GSLPRDFELSNYDCYGKPIEVNNGLGKPQAKNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFN 522

  Fly   515 LFFWT 519
            :.:|:
Mouse   523 VIYWS 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:273305	142/525 (27%)
		Neur_chan_LBD	36..259	CDD:280998	62/232 (27%)
		Neur_chan_memb	270..518	CDD:280999	72/277 (26%)
Glrb	XP_036018791.1	LIC	64..529	CDD:273305	142/525 (27%)
		LGIC_ECD_GlyR_beta	89..275	CDD:349811	55/203 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910