Protein Alignment CG6927 and Gabrd

DIOPT Version :9

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_006538609.2
• Gene: Gabrd / 14403
• MGIID: 95622
• Length: 483
• Species: Mus musculus
• Alignment Length: 561
• Identity: 142/561 - (25%)
• Similarity: 235/561 - (41%)
• Gaps: 133/561 - (23%)

  Fly     3 WSLIISILLNCLYASASALDEDCPTL------------------------------DDGD----- 32
            | |::.:||.|......|..:|...|                              |.||
Mouse     6 W-LLLPLLLLCTQPHHGARSKDPADLSPAARVLSAVLGAERCAVGRDWSRQARAMNDIGDYVGSN 69

  Fly    33 -SLSQTQLLDRLTHGCRYDRLERPITYSETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQM 96
             .:|....||.|..|  |.|..||....     .||:|.:...:..:.::...::::.:...|..
Mouse    70 LEISWLPNLDGLMEG--YARNFRPGIGG-----APVNVALALEVASIDHISEANMEYTMTVFLHQ 127

  Fly    97 RYLDPRLNFRNVSPKRRQPILG-EEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVI 160
            .:.|.||::.:.:     ..|| :....:.||:|..|:.|.:.:....:|.::.|..:.|||.::
Mouse   128 SWRDSRLSYNHTN-----ETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVIL 187

  Fly   161 VSNRIKATLYCWLNLKKFPFDEQHCSTVLESWMYNTSELVLHW-EQKRPITYDGALHLTEFVLQR 224
            .|.||.:|:.|.::|.|:|.|||.|...|||:.|::.::|.:| |.:..|.....|.|.:|.: .
Mouse   188 YSIRITSTVACDMDLAKYPLDEQECMLDLESYGYSSEDIVYYWSENQEQIHGLDRLQLAQFTI-T 251

  Fly   225 SWSNETVINADLSDLRHGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQ 289
            |:...|       :|.:...||.:..||....|.|..|.|::..::||:|:||:||||||:....
Mouse   252 SYRFTT-------ELMNFKSAGQFPRLSLHFQLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAA 309

  Fly   290 APPRITLGTSTLLTFITLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFV--NTIWRRK 352
            .|.|::||.:|:||..||..:...:||:.|.||..:|:|..|.:|:|.::||:||.  |..:|:|
Mouse   310 VPARVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKK 374

  Fly   353 KSVPVKKLNSKHILKSTLSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVN----- 412
            :...||               :.:.|:....|  :...|.      ||..||.:..|.::
Mouse   375 RKAKVK---------------VTKPRAEMDVR--NAIVLF------SLSAAGVSQELAISRRQGR 416

  Fly   413 LPITTIKEGQVLDQQRTSRVVQKMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNRTESAGH 477
            :|      |.::...|:..|..|.:..   |..|..|..:|
Mouse   417 VP------GNLMGSYRSVEVEAKKEGG---SRPGGPGGIRS------------------------ 448

  Fly   478 QEEIDLSGWTTLTPQEIAMWIDSRARFVFPLSFLVFNLFFW 518
                      .|.|.: |..||..||.|||.:|...|:.:|
Mouse   449 ----------RLKPID-ADTIDIYARAVFPAAFAAVNIIYW 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:273305	142/561 (25%)
		Neur_chan_LBD	36..259	CDD:280998	58/224 (26%)
		Neur_chan_memb	270..518	CDD:280999	68/254 (27%)
Gabrd	XP_006538609.2	LGIC_ECD	97..280	CDD:355788	50/195 (26%)
		Cys-loop	198..212	CDD:349787	7/13 (54%)
		LGIC_TM_GABAAR_delta	283..>371	CDD:349857	36/87 (41%)
		TM1 helix	286..306	CDD:349857	11/19 (58%)
		TM2 helix	315..336	CDD:349857	7/20 (35%)
		TM3 helix	346..368	CDD:349857	9/21 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900